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Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

BAF200 is essential for proper heart and coronary artery formation.

New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.

Estrogen therapy can reduce skin aging but has cancer risks.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.

Platelet-rich plasma (PRP) may improve healing in chronic wounds and vitiligo and promote hair regrowth, but more research is needed.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Variant G of the KRTAP20-1 gene improves wool curliness in Chinese Tan sheep.

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Minoxidil can cause heart muscle damage in dogs.

Minoxidil effectively controls blood pressure but side effects may limit its use.

These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.

Stress can trigger and worsen vitiligo.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

The patient's liver did not fully grow back and she had serious temporary side effects after a very large liver surgery.