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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Sebocytes play a key role in controlling androgen levels in human skin.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Minoxidil foam enters hair follicles and skin for hair growth.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.