research Adult-Onset Hair Loss in Chesapeake Bay Retrievers: A Clinical and Histological Study
Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.
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research CO2 Laser Treatment of Traumatic Tattoos
CO2 laser treatment successfully removed traumatic tattoos with minimal scarring.
research Smoothened Antagonists for Hair Inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Modulating Testosterone Pathway: A New Strategy to Tackle Male Skin Aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Recent Advances in the Medical and Surgical Treatment of Priapism
New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.
research A Method for the Determination of Minoxidil in Hair-Regrowth Formulations by Micellar Electrokinetic Capillary Chromatography
A quick and simple method was created to identify minoxidil in hair-growth products using micellar electrokinetic capillary chromatography.
research Melatonin Alleviates Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2/ROS/NLRP3 Pathway
Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.
research New Fluorogenic Probes for Neutral and Alkaline Ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Finasteride-Related Leydig Cell Tumor: Report of a Case and Literature Review
Finasteride use may be linked to rare testicular tumor, but more research needed.
research Immunosuppressive Therapy in Autoimmune Disease: A Review
Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Genetic Variation in the Ovine KAP22-1 Gene and Its Effect on Wool Traits in Egyptian Sheep
Certain genetic changes in the KAP22-1 gene are linked to better wool quality in Egyptian sheep.
research Good Efficacy Achieved by Baricitinib in the Treatment of Anti-MDA5 Antibody-Positive Dermatomyositis with Alopecia Areata
Baricitinib was effective in treating a patient with dermatomyositis and hair loss.
research Bicalutamide and the New Perspectives for Female Pattern Hair Loss Treatment: What Dermatologists Should Know
Bicalutamide, a drug with a good safety profile, is a promising new treatment for female pattern hair loss.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
research A Novel Regio-Specific Cyclosporin Hydroxylase Gene Revealed Through the Genome Mining of Pseudonocardia Autotrophica
Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.
research Transnasal Cooling: A Pandora’s Box of Transnasal Pathophysiology
Transnasal cooling could reveal new insights into various physiological conditions and may be a natural way to transfer heat from the brain.
research GSK-3 Inhibitors: Recent Developments and Therapeutic Potential
Drugs that block GSK-3 show promise for treating various diseases.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Ethanol Extract of Asiasari Radix Preferentially Induces Apoptosis in G361 Human Melanoma Cells by Differential Regulation of p53
Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.
research Identification of Llama KRTAP7-1 and KRTAP8-1 Fiber Genes and Polymorphism Screening
Mutations in specific llama genes may affect fiber quality for textiles.
research Can Beverages Grow Hair on Bald Heads?
Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
research Proteomic Analysis of Fetal Skin by iTRAQ Reveals Molecular Signals Underlying Inner Mongolia Cashmere Goat Hair Follicle Initiation
The research identified proteins that change as goat hair follicles begin to form, helping to understand how cashmere grows.
research Scaffolds for Epithelial and Hair Follicle Regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
research Human Biallelic MFN2 Mutations Induce Mitochondrial Dysfunction, Upper Body Adipose Hyperplasia, and Suppression of Leptin Expression
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
research Global Landscapes of Human Phenotypic Variation in Inherited Traits
Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
research Modulating Mechanosensory Afferent Excitability by an Atypical mGluR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.