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Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Early hormones shape sex-specific differences in rat glands.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Finasteride helps protect brain in old male rats.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Hair loss requires customized treatments based on its various causes and types.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Quercetin may help improve symptoms of polycystic ovary syndrome.