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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Anti-androgens can help reduce the effects of male hormones on the skin.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Clofazimine may be effective for treating ashy dermatosis.

Letrozole reduces seizures but not brain damage in mice.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Losartan can cause temporary loss of taste.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Finasteride may lower cholesterol and slow heart disease progression.