research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
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research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Risk of Acute Pancreatitis in Users of Finasteride
Finasteride doesn't raise acute pancreatitis risk.
research Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes
Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
research Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop
The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
research Genetic Variation at the MC1R Locus and the Time Since Loss of Human Body Hair
Humans lost body hair relatively recently in evolution.
research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture
IL-1β inhibits human hair follicle growth.
research Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection
Minoxidil protects heart and improves recovery.
research Care for Alopecia During Chemotherapy of Cancer Patients
The document concluded that there were no effective ways to prevent hair loss from chemotherapy but treatments were being explored.
research Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice
Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Augmentation of HGF Signaling: Potential for Enhancing Hair Follicle Neogenesis and Development in Bioengineered Skin
Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
research EZH2 Is Required for Human Hair Follicle Growth and Epidermal Differentiation
EZH2 is essential for hair growth and skin cell development.
research Is EBF1 a Negative Regulator of WNT10A in the Development of Androgenetic Alopecia?
Finasteride helps female-pattern hair loss.
research Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases
The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
research Establishment and Characterization of Human Sebocytic Progenitor Cells That Can Differentiate Into Functional Sebocytes
Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
research Hair Follicle Stem Cells in the Pathogenesis of the Scarring Process in Cutaneous Lupus Erythematosus
Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
research Efficacy and Safety of Baricitinib in Managing Severe Alopecia Areata: A 6-Month Real-World Experience
Baricitinib was effective and safe for severe hair loss treatment over 6 months.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
research Hair Follicle Targeting With Curcumin Nanocrystals: Influence of Formulation Properties on Penetration Efficacy
Curcumin nanocrystals in simple gels effectively penetrate hair follicles, but humectants can reduce this efficacy.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Healthy Hair: Form and Function
Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
research Frontal Fibrosing Alopecia: Clinical and Histopathological Characteristics of Mexican Patients - An Original Research Study and Review of Literature
Frontal Fibrosing Alopecia mainly affects postmenopausal Mexican women, requiring early detection to prevent permanent hair loss.
research Melasma and Endocrine Disorders
Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
research Diffuse Hair Loss Induced by Sertraline Use
Sertraline can cause hair loss, which stops after stopping the drug.
research Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System
Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
research Prevalence, Clinical Characteristics, Possible Etiological and Diagnostic Approach in Dogs with Acral Lick Dermatitis
The study concluded that Acral lick dermatitis is most common in young male Labrador retrievers, often caused by psychological factors, and leads to skin inflammation and stress-related blood changes.
research In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Minoxidil Induced Hair Growth After Leukemia Treatment
Minoxidil helped a boy regrow his hair after intense chemotherapy for leukaemia.
research Stepwise Acquisition of Unique Epigenetic Signatures During Differentiation of Tissue Treg Cells
Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.