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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Finasteride doesn't affect ovulation in normal women.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

The hemp extract significantly increased hair regrowth in both men and women without any side effects.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Stress can cause early aging in certain skin cells, leading to problems with hair growth.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.