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Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Testosterone's muscle-building effects do not require its conversion to DHT.