43 citations
,
February 2019 in “International immunology” This review examines the role of regulatory T cells in skin immune disorders, highlighting their unique functions in conditions like scleroderma, alopecia areata, and psoriasis, without reporting new clinical results.
43 citations
,
July 2016 in “European journal of pharmaceutical sciences” This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.
42 citations
,
January 2018 in “Expert review of precision medicine and drug development” This review discusses the integration of drug repurposing with personalized medicine through off-label prescribing and reports no new results, highlighting the potential for systematic exploration using omics technologies.
42 citations
,
July 2015 in “Cosmetics” This review discusses the use of cosmetic nanocarriers to improve hair appearance and reports no new experimental results.
41 citations
,
November 2024 in “Molecular Biomedicine” This review discusses the mechanisms and engineering techniques for enhancing the targeted delivery of extracellular vesicles in therapies but reports no new clinical findings; the authors encourage further exploration to advance clinical applications.
41 citations
,
August 2024 in “Drug Delivery and Translational Research” This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.
41 citations
,
January 2020 in “BioMed Research International” This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.
41 citations
,
September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
41 citations
,
June 2018 in “Medicine Health Care and Philosophy” This article proposes criteria to differentiate between medicalization and over-medicalization, examining the consequences and ethical considerations of misidentifying medical issues, and suggests guideline questions to help draw clearer boundaries in medicine.
41 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the benefits, techniques, and unique considerations of follicular unit extraction for hair grafting, but reports no new clinical results.
41 citations
,
March 1992 in “Archives of Dermatology” This review provides practical guidelines for managing psychodermatologic disorders and concludes that psychopharmacologic agents offer a useful option for treatment, considering the underlying psychopathologic condition.
40 citations
,
November 2021 in “npj Regenerative Medicine” In this study, spiny mice showed superior cardiac recovery after myocardial infarction compared to other mouse strains, with enhanced myocardial preservation and functional stabilization.
40 citations
,
November 2017 in “International journal of nanomedicine” In this study, the researchers reported that chloramphenicol-loaded liposomes, particularly those incorporating deoxycholic acid, enhanced follicular uptake and showed strong antibacterial activity against methicillin-resistant Staphylococcus aureus, offering potential for treating MRSA-infected skin conditions with good skin biocompatibility and minimal toxicity.
40 citations
,
January 2016 in “PLoS ONE” The study found that exposing Arbas Cashmere goats to a short photoperiod significantly increased cashmere production by extending the anagen phase of hair follicles, with gene expression changes identified as contributing factors.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
40 citations
,
July 2007 in “Dermatologic Therapy” This review discusses the pharmacologic properties, mechanisms, dosing options, and adverse effects of systemic glucocorticosteroids in dermatology, but reports no new findings.
39 citations
,
December 2018 in “Methods in molecular biology” This review discusses the data resources and computational models used in drug repositioning, highlighting their role in discovering unknown drug mechanisms and reports no new empirical results.
39 citations
,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
39 citations
,
November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
39 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article discusses the role of growth hormone, insulin, and IGF-1 in acne development and highlights how diet and syndromic evidence support their involvement, but presents no new clinical findings.
39 citations
,
January 2012 in “Reproductive Biology and Endocrinology” In this study, the prevalence of polycystic ovary syndrome among women seeking primary healthcare in Salvador, Brazil, was found to be 8.5% using the Rotterdam criteria.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
38 citations
,
September 2021 in “Signal Transduction and Targeted Therapy” This review discusses genetic factors contributing to susceptibility and outcomes in COVID-19, including ACE, ACE2, TMPRSS2 variants, HLA genotype, and ABO blood group, but reports no new experimental results.
38 citations
,
June 2018 in “Archives of Toxicology” This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.
38 citations
,
June 2018 in “Plant & cell physiology/Plant and cell physiology” This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.
38 citations
,
April 2016 in “Experimental Dermatology” This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.
38 citations
,
January 2016 in “Cell Death and Disease” This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.
38 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
37 citations
,
August 2016 in “Clinical, Cosmetic and Investigational Dermatology” This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.
37 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” This article discusses isotretinoin for severe acne vulgaris, noting its effectiveness but also highlighting significant side effects on skin, mucous membranes, and hair; it reports no new clinical results.