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sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Phospholipase A2 enzymes play key roles in skin health and disease.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The gene Prss53 affects hair shape and bone development in rabbits.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

ACBP is crucial for healthy skin in mice.

Genomic research can help improve the quality and production of natural fibers in animals.

The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Inhibiting PLA2 enzymes may help treat inflammatory skin diseases like psoriasis and dermatitis.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

New ginseng compounds may help treat degenerative diseases.

Researchers found 15 new genetic links to skin traits in Japanese women.