Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case study reported a postmenopausal woman with a testosterone-secreting ovarian tumor that was not detected through standard clinical or radiological examination but was found via biopsy.

This case report suggests that PCOS can present with virilization and rapidly increasing testosterone levels, and highlights oral contraceptives' effectiveness in managing hyperandrogenism in such cases.

This case report describes a 19-month-old girl with androgen-dominant virilization caused by an adrenal tumor, highlighting the importance of adrenal assessment in young girls with such symptoms and recommending long-term monitoring even after initial biochemical remission.

This case report describes a rare instance of hyperandrogenism and increased hirsutism associated with endometrial cancer in a postmenopausal woman, with symptoms resolving and androgen levels normalizing after a total laparoscopic abdominal hysterectomy and bilateral oophorectomy.

This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.

This case report suggests that ovarian steroid cell tumors should be considered in postmenopausal women with hirsutism and elevated testosterone, with surgery being effective in resolving symptoms and preventing recurrence.

This study suggests that metformin might serve as a diagnostic and therapeutic option to distinguish insulin resistance-related ovarian testosterone excess from a testosterone-secreting tumor in women with virilization.

This study identified several DPC-specific proteins, including ITGB1, IGFBP3, and THBS1, as potential biomarkers for hair growth modulation through proteomic and network analysis.

In this study, researchers showed that Wnt ligands secreted by hair follicle epithelium are crucial for hair follicle regeneration and may be significant for treating hair disorders like alopecia.

This review discusses the potential of stem cell secretome in regenerative medicine and suggests that its paracrine effects, rather than direct cell replacement, may drive therapeutic benefits.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

This study found that surgical normalization of testosterone in hyperandrogenic women with ovarian androgen-secreting tumors did not significantly change body weight or insulin sensitivity after 12 months.

This case report describes a testosterone- and cortisol-secreting adrenocortical oncocytoma causing hirsutism in a 23-year-old woman, highlighting adrenal oncocytomas as an important consideration for differential diagnosis.

This study found that one session of intradermal botulinum toxin type A injection decreased scalp sebum secretion and perception of greasiness more effectively than saline for up to 3 months.

This study found that combining ISX-9 with mesenchymal stem cells enhanced their ability to reduce inflammation and repair lung damage in an acute lung injury model compared to using the cells alone.

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This study demonstrated that treating platelet-rich plasma with ozone or procaine in vitro led to distinct changes in platelet activity, significantly enhancing the release of platelet-derived factors without damaging the platelets, indicating potential for improved regenerative therapies.

This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.

In this study, the authors reported that combining PMSC-secretome and Wnt10b in a GelMA hydrogel scaffold promoted effective hair follicle biofabrication and hair growth in a small in vivo experiment. They emphasized the need for larger studies to confirm these results.

This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.

This study found that inhibiting prolactin secretion during the telogen phase can reduce the number of activated secondary hair follicles and the width of hair bulbs.

This case study reports a patient with ACTH-driven cortisol secretion 14 years after adrenalectomy, suggesting possible residual adrenal tissue or extra-adrenal steroid synthesis, challenging the need for lifelong steroid replacement.

This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.

Electric current quickly reduces hand sweating but the effect doesn't last long.

This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.

This study investigated how secretions from cultured human hair follicle-derived keratinocytes affect gene expression in human follicle dermal papilla cells to understand their signaling interactions.

This study found that allopregnanolone has a bimodal effect on prolactin secretion in sheep, stimulating PRL mRNA expression but inhibiting hormone release under stress and pregnancy conditions.

This study found that platelet-derived growth factor secretion in PRP therapy for alopecia is highly variable between patients, which may contribute to inconsistent clinical responses.

This case report describes the first known instance of a testosterone-secreting steroid cell ovarian tumor causing pulmonary embolism and erythrocytosis in a postmenopausal woman, highlighting its potential role as a rare cause of hypercoagulable state.

This case report describes a young woman with an adrenal oncocytic tumor of uncertain malignant potential, highlighting the need for ongoing surveillance due to possible malignancy.