343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
70 citations,
January 2000 in “Hormone Research in Paediatrics” SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
66 citations,
April 2016 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
59 citations,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
45 citations,
January 2016 in “Dermatologic Clinics” Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.
45 citations,
January 2008 in “Drugs” Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
36 citations,
February 2019 in “American Journal of Clinical Dermatology” Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.
35 citations,
May 2020 in “Frontiers in Pharmacology” Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
29 citations,
January 2013 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
27 citations,
October 2018 in “Journal of optometry” Eyelashes protect the eyes, but more research is needed to understand how.
24 citations,
July 2018 in “Journal of Molecular Endocrinology” The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
16 citations,
May 2011 in “Journal of The American Academy of Dermatology” Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.
15 citations,
March 2018 in “Clinics in Dermatology” Elderly abuse is often by family members, and doctors, especially dermatologists, can spot it by looking for unusual injuries and malnutrition.
8 citations,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
5 citations,
January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
3 citations,
January 2010 in “Expert Opinion on Pharmacotherapy” No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
3 citations,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
June 2022 in “Evidence-based complementary and alternative medicine” Acupressure improves quality of life in PCOS patients.
July 2017 in “Cardiologia Croatica” Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.
April 2014 in “Fertility and Sterility” The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
Hair loss can cause significant social and emotional issues, especially for women and young men.
176 citations,
August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
160 citations,
April 2008 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” DHT in the human prostate is produced through multiple pathways, not just from testosterone.
2 citations,
December 2021 in “International Journal of Andrology” Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.
June 2023 in “Clinical and Experimental Dermatology” Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.
16 citations,
February 2014 in “Iranian Red Crescent Medical Journal” Polycystic Ovary Syndrome (PCOS) affects Iranian women's feelings of femininity and self-image.
1 citations,
February 2024 in “Environmental health perspectives” Exposure to certain metals may worsen attention-related behaviors in adolescents, with stronger effects in females.
March 2024 in “BMC women's health” The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.