505 citations,
December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
71 citations,
May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” TTD hair brittleness is caused by multiple structural abnormalities.
64 citations,
January 2009 in “Canadian Journal of Gastroenterology” Interferon and ribavirin can cause serious skin reactions and other health issues.
51 citations,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
30 citations,
September 2020 in “Journal of Patient-Reported Outcomes” Alopecia Areata (AA) causes significant emotional distress, including feelings of embarrassment, depression, and anxiety, and impacts social interactions and daily activities.
26 citations,
January 2018 in “Skin appendage disorders” Thallium, mercury, selenium, and colchicine strongly cause hair loss.
11 citations,
September 2021 in “American Journal of Medical Genetics Part A” Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.
10 citations,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” Alopecia areata greatly affects people's life quality, mental health, and work life.
8 citations,
September 2021 in “Skin appendage disorders” Trichotillomania treatment is most successful with a mix of behavioral therapy, medication, and social support.
8 citations,
January 2016 in “Cells tissues organs” Norepinephrine helps skin cells grow, which is important for hair growth.
7 citations,
November 2021 in “JAAD Case Reports” Mogamulizumab can cause hair loss and skin rashes.
7 citations,
January 2017 in “Clinical and medical investigations” Suriname uses many plants for beauty, with potential for a beauty industry, but more evidence is needed for product effectiveness.
6 citations,
May 2023 in “Drugs” Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.
6 citations,
May 2022 in “Frontiers in Microbiology” Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.
6 citations,
November 2020 in “Clinical Cosmetic and Investigational Dermatology” Both concentrations of triamcinolone acetonide are effective for hair regrowth in patchy alopecia areata, but 5 mg/mL is recommended to reduce side effects.
6 citations,
May 2019 in “JAMA Facial Plastic Surgery” Removing certain muscles during a browlift reduces glabellar wrinkles better long-term.
3 citations,
November 2021 in “World Journal of Clinical Pediatrics” Vitamin D might help treat some types of hair loss, but more research is needed.
2 citations,
January 2021 in “Indian Journal of Dermatology, Venereology and Leprology” Betamethasone is more effective for hair regrowth than latanoprost but has more side effects.
2 citations,
June 2016 in “PubMed” An 11-year-old girl with compulsive hair pulling was successfully treated with therapy and medication.
1 citations,
November 2023 in “International journal of molecular sciences” Cannabinoids might help treat skin problems but more research is needed to be sure.
1 citations,
February 2022 in “Biological Trace Element Research” The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
1 citations,
January 2018 in “Indian journal of dermatopathology and diagnostic dermatology” Trichoscopy helps diagnose and monitor hair and scalp problems without needing many biopsies.
August 2024 in “Journal of Clinical Medicine” Systemic treatments like hydroxychloroquine and cyclosporine A help with Lichen Planopilaris and Frontal Fibrosing Alopecia, but ongoing treatment is needed.
April 2024 in “Pharmaceuticals” Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.
December 2023 in “Journal of clinical medicine” Some leukemia treatments can cause skin reactions similar to keratosis pilaris.
November 2023 in “BMC genomics” The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.
July 2023 in “Journal of Clinical Medicine” The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
April 2023 in “JOJ dermatology & cosmetics” The conclusion is that a team of skin doctors and psychiatrists is needed to better treat patients with mind-skin disorders.
Seborrheic dermatitis and dandruff are often treated with antifungal and anti-inflammatory medications, which can reduce symptoms and yeast growth on the scalp.
March 2022 in “Wound practice & research” New treatments for alopecia areata show promise, but standardized guidelines are needed.