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Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Excessive blue light harms eye cells and disrupts sleep patterns.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

New therapies show promise for wound healing, but more research is needed for safe, affordable options.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Msx2 and Foxn1 are both crucial for hair growth and health.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Further research is needed to understand how the microbiome affects hair loss in Alopecia Areata.

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.