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The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

Artificial sebum L closely mimics human sebum for drug delivery research.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.

Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.

Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.

Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.

Polymeric nanoparticles show promise for treating skin diseases.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.

A dog fully recovered from minoxidil poisoning after receiving treatment.