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The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Microemulsions could improve how drugs are delivered and absorbed in the body.

Finasteride cream helps hair growth with less side effects.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Hair lipids do not protect against humidity.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.

An adult woman with scalp infection recovered after antifungal treatment, with no return of symptoms.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Hair analysis is better than urine and blood for detecting past drug use.

Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.