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The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

People with Major Depressive Disorder have a higher chance of getting Alopecia Areata, and vice versa; antidepressants may lower this risk.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

CCCA is a common scarring hair loss in African descent women, possibly linked to genetics, hair care practices, and health issues like diabetes.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Long-term etretinate use may cause delayed wound healing and extra tissue growth after injury.

Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.

Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

Hibiscus rosa sinensis shows promise for treating various health conditions and promoting hair growth.

A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

FA2H is essential for normal fur and sebum production in mice.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.

The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.

Sebum helps protect human skin from microbes.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.