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      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      Signaling Involved in Hair Follicle Morphogenesis and Development

      research Signaling Involved in Hair Follicle Morphogenesis and Development

      223 citations , January 2014 in “International Journal of Molecular Sciences”
      This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
      More Than One Way to Skin

      research More than one way to skin . . .

      218 citations , April 2008 in “Genes & Development”
      This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.
      Gender-Linked Differences in Human Skin

      research Gender-linked differences in human skin

      205 citations , July 2009 in “Journal of Dermatological Science”
      This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
      Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      178 citations , August 2016 in “Advances in wound care”
      This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      Endocrinology of Transgender Medicine

      research Endocrinology of Transgender Medicine

      166 citations , October 2018 in “Endocrine Reviews”
      This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
      Low-Level Laser Therapy for Treatment of Hair Loss

      research Low‐level laser (light) therapy (LLLT) for treatment of hair loss

      165 citations , August 2013 in “Lasers in Surgery and Medicine”
      This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      Epithelial Stem Cells And Implications For Wound Repair

      research Epithelial stem cells and implications for wound repair

      156 citations , October 2012 in “Seminars in Cell & Developmental Biology”
      This study found that hair follicle stem cells initially contribute to wound re-epithelialization, but long-lasting epidermal cells are primarily derived from a stem cell population in the isthmus portion of hair follicles.
      Molecular Biology of Hair Morphogenesis: Development and Cycling

      research Molecular biology of hair morphogenesis: Development and cycling

      155 citations , August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution”
      This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Gender Differences in Skin: A Review of the Literature

      research Gender differences in skin: A review of the literature

      152 citations , December 2007 in “Gender Medicine”
      This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
      Estrogens and Aging Skin

      research Estrogens and aging skin

      150 citations , April 2013 in “Dermato-endocrinology”
      This review discusses the effects of estrogen on skin aging and highlights potential therapies, but reports no new clinical findings.
      EEMCO Guidance for the In Vivo Assessment of Skin Greasiness

      research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

      137 citations , January 2000 in “Skin Pharmacology and Physiology”
      This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
      Stem Cell Dynamics in the Hair Follicle Niche

      research Stem cell dynamics in the hair follicle niche

      135 citations , December 2013 in “Seminars in Cell & Developmental Biology”
      This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.
      Acne, the Skin Microbiome, and Antibiotic Treatment

      research Acne, the Skin Microbiome, and Antibiotic Treatment

      134 citations , January 2019 in “American journal of clinical dermatology”
      This review summarizes recent research on the skin microbiome's role in acne development and how antibiotic treatments affect skin microbes, but it reports no new clinical results.
      TRP Channels in Skin Biology and Pathophysiology

      research TRP Channels in Skin Biology and Pathophysiology

      124 citations , December 2016 in “Pharmaceuticals”
      This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.