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Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Enhancing cannabinoid signaling may help treat skin inflammation.

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Activating TRPV3 reduces skin oil production and increases inflammation, potentially causing dry skin issues.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.

Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Dandruff and seborrheic dermatitis are caused by yeast feeding on scalp oils, leading to irritation and flaking.

Myc activation reduces skin stem cells by affecting cell adhesion.

Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

ACBP is crucial for healthy skin in mice.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.