29 citations
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March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
12 citations
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May 2017 in “Journal of Dermatological Treatment” This study found that in adults over 25, stress from lifestyle changes, sensitive skin, stopping oral contraceptives, and the use of full-coverage foundations were associated with increased severity of acne.
11 citations
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January 2018 in “Royal Society Open Science” This study investigated the formation of Type III brush hair in Chinese Haimen goats and identified genetic factors that may involve heat stress in the process.
8 citations
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October 1989 in “International Journal of Dermatology” This review discusses the role of Cytochrome P-450 in dermatology and reports no new clinical results.
7 citations
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January 2019 in “Postepy Dermatologii I Alergologii” This study found that the count of CAG trinucleotide repeats in the androgen receptor gene may be associated with acne in female patients without hyperandrogenism.
7 citations
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January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
7 citations
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January 2013 in “BioMed research international” This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.
6 citations
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March 2011 in “Experimental Dermatology” This study found that an imbalance of selenium in a C57BL/6 mouse model led to hair loss with color change and was linked with changes in hair follicle apoptosis markers.
research Acne
4 citations
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January 2019 This analysis examines acne vulgaris using an integrative approach, highlighting its links with psychopathology, lifestyle, and diet, but reports no new results.
3 citations
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January 2012 in “Wageningen Academic Publishers eBooks” This article discusses the complex biological functions and social significance of hair follicles and reports no new research findings, emphasizing their role in health, disease, and a substantial beauty industry.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.
August 2023 in “Repository of the University of Primorsk (University of Primorska)” A Western diet may increase acne risk, while a Mediterranean diet and certain supplements can help reduce it.
October 2022 in “Boletín médico del Hospital infantil de México/Boletín médico del Hospital Infantil de México” This case report describes an 18-year-old male with a rare acquired smooth muscle hamartoma on his face, characterized by hyperpigmented plaques and increased hair growth, suggesting a histological overlap with folliculosebaceous cystic hamartoma.
September 2017 in “Journal of Investigative Dermatology” This study suggests that sweat glands may have an immune privilege similar to hair follicles, and disruptions in this could contribute to autoimmune skin diseases.
This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.
April 2021 in “Journal of Investigative Dermatology” This study developed a transgenic mouse model to explore androgenetic alopecia, finding that inducible COX2 expression led to sebaceous gland changes and hair miniaturization, with reversible effects upon reducing COX2.
March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
137 citations
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January 2000 in “Skin Pharmacology and Physiology” This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
35 citations
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May 2012 in “Expert Opinion on Pharmacotherapy” This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.
25 citations
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September 2006 in “Birth Defects Research” This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.
October 2018 in “InTech eBooks” This research suggests that mouse mutants and genomics can help study hair biology and epithelial differentiation by focusing on the role of the Foxn1 gene.
43 citations
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April 2010 in “Developmental Biology” In this study, researchers observed that the sebaceous gland niche in mice allows for Wnt-induced hair follicle differentiation, unlike the non-permissive bulge.
45 citations
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August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
85 citations
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June 2017 in “Journal of Investigative Dermatology” This study found that Blimp1 plays a key role in promoting hair follicle morphogenesis and growth by mediating inductive signaling pathways in dermal papilla cells.
26 citations
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March 2018 in “Experimental Dermatology” This article argues that prolactin may have a role in sebaceous gland function and suggests it could be a potential target for treating skin conditions, but reports no new clinical findings.
June 2024 in “Journal of Allergy and Clinical Immunology” In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.
12 citations
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January 2009 in “Stembook” This review addresses the limitations of current engineered skin substitutes for burn patients and highlights potential improvements through stem cell biology and skin morphogenesis, but it reports no new clinical results.
201 citations
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May 2001 in “Proceedings of the National Academy of Sciences” This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.