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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

FA2H is essential for normal fur and sebum production in mice.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New acne treatments show promise as alternatives to traditional therapies.