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Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Stem cells could improve hair growth and new treatments for baldness are being researched.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Dog hair follicle stem cells can turn into fat cells.

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.

Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

Advancements in hair biology include new treatments and tools for hair growth and alopecia.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Fat-related cells are important for initiating hair growth.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Lactate production is important for activating hair growth stem cells.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.