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Understanding skin structure and development helps diagnose and treat skin disorders.

High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

A 5-year-old Akita with a rare skin condition improved significantly after treatment.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The dog had sebaceous adenitis, treated with ciclosporin, leading to some hair regrowth.

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Neuregulin3 affects cell development in the skin and mammary glands.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

The study found unique skin changes in a rare type of alopecia linked to a skin condition called linear morphea.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

ACBP is crucial for healthy skin in mice.

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.