research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin
Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
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research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Hormonal Treatment of Acne Vulgaris: An Update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Acneiform Dermatoses
Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.
research The Non-Neuronal and Nonmuscular Effects of Botulinum Toxin: An Opportunity for a Deadly Molecule to Treat Disease in the Skin and Beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Aging in Hair Follicle Stem Cells and Niche Microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-Regulate Their TLR-2 and TLR-4 Expression
ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
research Polyamines and Hair: A Couple in Search of Perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research Non-Rash Skin Toxicities Associated with Novel Targeted Therapies
Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Hormonal Therapy in Dermatology
Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
research Stem Cells Behind the Barrier: Mechanisms Regulating Epidermal Stem and Progenitor Cell Differentiation
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Alopecia
The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
research Role of Bulge Epidermal Stem Cells and TSLP Signaling in Psoriasis
Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
research Chemotherapy-Induced Iatrogenic Injury of Skin: New Drugs and New Concepts
New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
research A Comparative Study of Cutaneous Manifestations of Hyperandrogenism in Obese and Non-Obese Taiwanese Women
Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.
research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study
Keratoacanthoma comes from hair follicle cells.
research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia
Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Idiopathic Hirsutism: Excessive Bodily and Facial Hair in Women
Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.
research Update: The Pathogenesis and Treatment of Polycystic Ovary Syndrome
New treatments for PCOS focus on managing symptoms and improving fertility.
research Polycystic Ovary Syndrome: Features, Diagnostic Criteria, and Treatments
PCOS is a long-term condition that needs more research for better understanding and treatment.
research Metabolism and Skin Diseases
Skin health and diseases are closely linked to metabolic processes.