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Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Blocking a specific protein signal can make hair grow on mouse nipples.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Dirty dots are a common scalp finding in elderly women and can be washed away with shampoo.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Near-infrared laser therapy with Indocyanine Green dye improves acne by reducing inflammation without side effects.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

A 29-year-old man had a jaw plaque diagnosed as follicular mucinosis, linked to nestin-positive hair follicle stem cells.