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The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cathepsin L is essential for normal hair growth and development.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Mutant mice help researchers understand hair growth and related genetic factors.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Sex hormones, especially androgens, play a key role in causing acne.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Edar signaling is crucial for proper hair follicle development and function.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Benign follicular mucinosis involves immune cells attacking hair follicles.

Dupilumab may cause significant hair loss, which can reverse after stopping the drug.

Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

New method uses hair follicles to deliver drugs deep into the skin.

Without keratin 10, there's more growth and development of oil-producing skin cells.