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Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

A man's chest hair turned white after a shingles infection, possibly due to virus-damaged pigment cells.

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

Killing specific cells in hair follicles can lead to hair growth problems in mice.

Women with hair loss have more androgen receptors in certain hair follicles.

CBD can either promote or inhibit hair growth depending on the concentration used.

Pellagra, caused by niacin deficiency and presenting with photosensitivity, should be considered in patients with relevant symptoms and risk factors.

Effective acne treatment varies by type, with topical and oral medications showing strong evidence, and patient education and support are crucial.

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

Blocking CCR5 can prevent and improve hair loss in alopecia areata.

Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.

Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Sebocytes play a key role in controlling androgen levels in human skin.

K6hf is a unique protein found only in a specific layer of hair follicles.