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This study found that in women with acne vulgaris, lower serum levels of 3α-androstanediol-glucuronide suggest reduced 5α-reductase activity compared to controls, indicating that 5α-reductase inhibitors may not be effective for acne treatment.

This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.

In this study, researchers prepared a herbal hair tonic using virgin coconut oil and nine herbs, evaluating its antibacterial, antifungal activities, and benefits for hair strength, with variations in ingredient concentrations and analyses for consistency and appearance.

This study explores the medicinal and environmental applications of Physalis species, highlighting the wound healing properties of Physalis angulata L. and the antibacterial and antitumor activities of its fruit extracts.

This study found that newly synthesized steroidal trienones demonstrated stronger 5α-reductase inhibitory activity compared to dienones in various biological models, suggesting potential for developing enhanced antiandrogenic drugs.

This article explores how natural and man-made factors shape architecture and environments for human activity in emergency situations, focusing on the unique conditions of the Republic of Kazakhstan. Results are not reported.

This case report describes a woman with Becker's nevus and ipsilateral breast hypoplasia who showed breast enlargement after one month of spironolactone treatment, suggesting a link between hypoplasia and increased androgenic receptor activity.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.

This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.

This study found that RANK-RANKL signaling regulates hair renewal and epidermal homeostasis in mice, revealing its role in initiating hair growth cycles and maintaining skin cell activity.

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

This study found that human scalp hair follicles can internally operate a Cori cycle, synthesize glycogen in the presence of lactate, and modulate growth through glycogen phosphorylase activity.

This study found that melatonin implants advanced the timing of the spring moult and increased hair follicle activity in adult cashmere goats, but had no significant effects on juvenile goats.

This study investigated single-cell changes in photoaged skin, revealing distinct cell clusters and increased activity in PD-L1 and PD-1 pathways in sun-exposed areas, enhancing understanding of UVA-induced skin damage and potential prevention targets for photoaging and UV-induced skin cancers.

In this study, the researchers developed and evaluated eco-friendly poly-herbal soap strips using plant extracts from Lantana camara, Moringa Oleifera, and Corn silk, finding that the strips exhibited superior physicochemical properties and significant anti-fungal activity compared to conventional anti-fungal soaps.

This study found that cashmere goats with greater fasted live-weight gain during the non-growing period had increased cashmere yield and staple length, likely due to higher secondary hair follicle activity.

Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.

This study suggests that typical skin lesions in Carney complex may originate from the pro-melanogenic activity of a specific dermal fibroblast population influenced by PKA signaling.

This review discusses the potential of phytochemicals from plants as alternative treatments for prostate cancer, highlighting their possible benefits over current 5-alpha-Reductase inhibitors, but reports no new findings.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

In this study, biotin supplementation was found to significantly increase wool follicle viability and metabolic activity in vitro, with the highest effects observed at 0.5 mg L⁻¹ concentration.

In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.

This review highlights the beneficial effects of certain herbal drugs in treating skin diseases, such as their healing, antifungal, antiviral, antibacterial, anti-inflammatory, and antitumor-promoting activities, emphasizing recent technical advancements in the field over the past 17 years.

This study prepared herbal hair oil using ingredients like coconut oil, amla, neem, hibiscus, and onion, and reported that the formulations exhibit anti-hairfall properties along with benefits like antidandruff activity, improved scalp circulation, and reduced hair whitening compared to synthetic alternatives.

This study found a perfect correlation between laser Doppler velocimetry measurements of scalp blood perfusion after minoxidil application and sulfotransferase enzyme activity in hair follicles, indicating a potential non-invasive test to predict minoxidil response in female pattern hair loss.

This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.

This study found that quiescence in hair follicle stem cells acts as a tumor suppression mechanism for cutaneous squamous cell carcinoma, with Pten activity necessary to maintain this state.

The study found that melatonin treatment in early postnatal cashmere goats increased both the quantity and quality of cashmere by promoting secondary hair follicle development and enhancing antioxidant enzyme activities.