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Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Polymeric nanoparticles show promise for treating skin diseases.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different types of skin cells play specific roles in development, healing, and cancer.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lactate production is important for activating hair growth stem cells.