36 citations,
December 2014 in “F1000 prime reports” The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.
35 citations,
November 2021 in “Journal of nanobiotechnology” Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
33 citations,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
24 citations,
November 2015 in “International Journal of Cosmetic Science” Treating scalp issues with anti-dandruff shampoo improves hair health.
21 citations,
May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
19 citations,
November 2017 in “General and comparative endocrinology” BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
15 citations,
December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
7 citations,
September 2017 in “Biomedical and Pharmacology Journal” Growth factors greatly affect hair loss, with different levels seen in men, women, younger patients, and at the start of the condition.
6 citations,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
3 citations,
September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
2 citations,
August 2023 in “Pharmaceutics” New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.
1 citations,
March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
1 citations,
January 2022 in “Journal of Biosciences and Medicines” Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
June 2024 in “Infection and Drug Resistance” An adult woman with scalp infection recovered after antifungal treatment, with no return of symptoms.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.
May 2023 in “Frontiers in Endocrinology” Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
March 2019 in “SLAS TECHNOLOGY” New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
October 2022 in “The Korean Journal of Physiology and Pharmacology” Targeting the PGD2-DP2 pathway may help treat hair loss.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
328 citations,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
136 citations,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
91 citations,
February 2009 in “Journal of biological chemistry/The Journal of biological chemistry” DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
74 citations,
October 2015 in “Experimental Dermatology” Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
64 citations,
January 2009 in “The International journal of developmental biology” Hair follicle stem cells are controlled by their surrounding environment.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
53 citations,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.