Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report presents a 14-year-old girl with type A insulin resistance, illustrating diagnostic processes to differentiate it from type 2 diabetes in the context of pediatric obesity and hyperglycemia.

This paper reviews the current lack of evidence on the safety and effectiveness of gender-affirming therapies in minors with gender dysphoria, highlighting ethical and legal concerns, including possible long-term consequences such as infertility.

This narrative review found a strong association between alopecia areata and autoimmune thyroid diseases, suggesting routine thyroid function and autoantibody screening could be beneficial for certain patients with extensive, recurrent, or early-onset alopecia areata.

This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.

This study found that genes such as FGF5, FGFR1, and RRAS may impact the growth cycle of secondary hair follicles in Inner Mongolian Cashmere goats.

Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.

This paper reviews obesity diagnosis and screening methods, emphasizing BMI's practicality in low- and middle-income countries, but provides no new clinical results.

This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.

This review discusses medical interventions that reproductive health experts can provide to transgender and gender diverse youth and reports no new clinical results.

This review summarizes evidence and adverse event management recommendations for Sacituzumab Govitecan in metastatic triple-negative breast cancer and hormone receptor-positive breast cancer, emphasizing favorable survival data from clinical trials.

This review details the 2023 International Guideline update for assessing and managing polycystic ovary syndrome, which provides evidence-based recommendations to improve care and patient outcomes but notes the remaining low to moderate quality of evidence.

This review discusses the 2023 International Guideline for PCOS assessment and management, highlighting updated evidence-based recommendations and practice points aimed at improving care and health outcomes, but notes that research quality remains generally low to moderate.

This study found a recurrent nonsense mutation in the HR gene linked to atrichia with papular lesions in two Kashmiri families, suggesting whole exome sequencing as an efficient method for diagnosis and genetic counseling.

This article highlights the need for dermatologists to define evidence-based standards to provide high-value care and reduce unnecessary testing, as recommended by the American Academy of Dermatology.

This case report described a young Himalayan kitten in Indonesia with notoedric mange, treated successfully with topical selamectin and sarolaner, highlighting the importance of early diagnosis and management to prevent reinfestation, especially in urban areas.

This study by a panel of 13 clinicians led to 22 consensus statements recommending approaches for diagnosing scarring and nonscarring alopecias, suggesting scalp biopsy for suspected scarring alopecias and specific serologic tests for nonscarring types like alopecia areata based on clinical presentation.

This research found that translucent keratin films absorbed more dye than opaque films, suggesting they may serve as better screening substrates for evaluating hair dye effectiveness.

This review discusses the unique healthcare needs and disparities faced by transgender individuals, highlighting the importance of cultural competency and skills in providers, but reports no new clinical findings.

This article discusses the updated European Training Requirements for the specialty of Dermatology and Venereology, emphasizing the harmonization of curriculum to improve specialist training across Europe, and reports no new clinical results.

This consensus from 22 Spanish dermatologists recommends using a multimodal therapy starting with oral dutasteride, combined with topical and/or intralesional agents, and adding hydroxychloroquine if inflammation persists, to manage frontal fibrosing alopecia due to its irreversible hair loss and lack of specific approved treatments.

This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.

This review discusses the need for an updated 'European hair cosmetic series' to include common contact allergens and remove outdated substances based on current evidence and regulations, but it reports no new results.

This study discusses the challenges in translating organoid models from laboratory settings to clinical and commercial applications, emphasizing the need for engineering approaches like environmental recapitulation and matrix engineering to bridge this gap.

In this study, the researchers performed a comparative analysis of drug-target interaction data from multiple databases to refine drug repurposing strategies, revealing potential associations between drug characteristics and therapeutic groups, and predicting repositioning opportunities for FDA-approved drugs across major cancer types.

This study found a significant prevalence of autoimmune gastritis among iron deficiency patients, suggesting guidelines should include non-invasive testing for this condition during initial evaluations.

This article discusses common myths about cancer, such as surgery causing metastasis, which can impact patient decisions and adherence to treatments, but reports no new results.

This study identified five FDA-approved drugs—cepharantine, clofazimine, metergoline, imatinib, and efloxate—as potential candidates for repurposing to interfere with viral entry in COVID-19 treatment.

This review notes that while ATX-101 showed a favorable safety profile for reducing submental fat in clinical trials, serious adverse events related to procedures have been reported in real-world use, prompting recommendations for improved management and prevention strategies.

In this study, aqueous and aqueous-alcoholic extracts of Ajuga reptans showed promising hepatoprotective and wound-healing properties, with significant effects observed in experimental models, suggesting potential for development into official medicinal products pending further research.

This review discusses the disproportionate negative impact of the COVID-19 pandemic on individuals with chronic medical conditions and calls for strategies to protect these vulnerable populations.