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Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

FOXN1 gene variants cause low T cells and immune issues from birth.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Bimatoprost is safe but not effective for severe eyelash loss from alopecia areata, possibly helping those with less loss.

Diphencyprone treatment increases CD8 lymphocytes in the scalp, which is associated with hair regrowth in alopecia areata patients.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

A rare genetic mutation found in an Indian family can be detected through prenatal screening.

Hair from balding and non-balding areas regrows similarly on mice.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.

Sertraline can cause hair loss, which stops after stopping the drug.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Artemis protein may help control hair growth and health by influencing cell processes.

Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.