This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.
December 2025 in “Journal of AI” This study bibliometrically evaluated 5741 articles on PRP from 1980 to 2024, highlighting Türkiye's contribution and identifying prominent research areas such as orthopedics and wound healing.
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
January 2025 in “Advances in Clinical Medicine” This review summarizes research on the use of Platelet-Rich Plasma for treating discogenic low back pain, showing potential therapeutic benefits but indicating varied results across studies and a need for more objective evaluation methods.
This literature review reports that mesenchymal stem cell-derived secretome, including conditioned medium and extracellular vesicles, shows promise as an effective treatment for various diseases in animal and human in-vivo models, with ongoing clinical trials and recommendations for future research discussed.
March 2024 in “Tropical Journal of Natural Product Research” This study surveyed the use and potential toxicity of medicinal plants in the Fez-Meknes region of Morocco, documenting 59 toxic species used primarily for cosmetic purposes and minor illnesses, and identified hair loss and rheumatism as having the highest informant agreement ratios.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.
The study found that conditioned medium from placental cells and sub-cultured placental tissue promoted angiogenesis in HUVECs, with early pregnancy cells showing more significant effects than those from full-term pregnancy.
This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.
This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
September 2011 in “Clinical Biochemistry” This study indicated that a novel calcium-phosphate nanoflower coating on titanium surfaces had high surface area, low cytotoxicity, and promising cell affinity, suggesting it could be a potential alternative modification method for titanium implants.
This study found that low-level laser therapy (LLLT) may enhance hearing recovery after noise-induced hearing loss in rats.
January 2008 in “Durham e-Theses (Durham University)” This study observed that stem cells from the hair follicle dermis share similarities with bone marrow-derived mesenchymal stem cells and have potential to form neural-like cells under specific conditions.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
45 citations
,
September 2012 in “Life Sciences” This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.
21 citations
,
April 1990 in “Journal of comparative neurology” This study found that the spinal projection of afferents innervating slowly adapting mechanoreceptors had a greater rostrocaudal extent and number of boutons compared to those innervating rapidly adapting mechanoreceptors.
18 citations
,
June 2018 in “Journal of The American Academy of Dermatology” This review found that existing studies on adipose tissue for scarring, wound healing, and hair growth show some positive outcomes, but the evidence is insufficient to change current dermatological practices.
14 citations
,
May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
January 1999 in “Current Problems in Pediatrics” Swimming in Lake Malawi can lead to schistosomiasis, hepatitis B vaccine might cause temporary hair loss, and certain drinks affect kidney stone risk.
49 citations
,
July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
29 citations
,
January 2016 in “CNS drugs” This review of teriflunomide for relapsing-remitting multiple sclerosis examines its clinical and safety outcomes, finding it significantly reduces relapse rates and disability progression while being generally well-tolerated.
15 citations
,
September 2018 in “Indian Research Journal of Pharmacy and Science” This article reviews the historical and therapeutic aspects of aromatherapy, discussing its effects on psychological and physical well-being but providing no new clinical findings.
2 citations
,
January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
March 2026 in “Quality in Sport” This review evaluates photobiomodulation's diverse clinical uses in sports and medicine, reporting physiological modulation and potential therapeutic benefits, but emphasizes the importance of precise dosimetry for success.
October 2023 in “Cognizance journal” This study explores using agent-based modeling and nutrition science to predict and treat oral and dental diseases as alternatives to traditional incarceration for managing criminal behavior, but results are not reported.
40 citations
,
November 2016 in “Molecules” This review discusses the historical and current use of ribosome-inactivating protein-expressing plants in traditional medicine across various cultures and regions, highlighting their role despite a lack of scientific validation.
July 2024 in “Open Repository of the University of Porto (University of Porto)” Dutasteride is more effective than finasteride for hair growth, and pregabalin effectively treats neuropathic pain.
4 citations
,
August 2015 in “PloS one” This study found that whisker follicle stem cells transplanted to injured spinal cords in mice contributed to healing and unexpectedly grew hair at the injury site.
13 citations
,
December 2010 in “Pharmacology Biochemistry and Behavior” Inhibiting certain enzymes made female rats more sensitive to low-level pain.