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    Glossary Schwann cells

    specialized cells that insulate and support peripheral nerve fibers

    Schwann cells are specialized cells in the peripheral nervous system that wrap around nerve fibers to form the myelin sheath, which insulates the nerves and speeds up the transmission of electrical signals. They play a crucial role in nerve regeneration and repair by providing support and nutrients to neurons.

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    Research 30 of 564

    1. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves Proceedings of the National Academy of Sciences · 2005 · 319 citations
    2. Macrophages Regulate Schwann Cell Maturation after Nerve Injury Cell Reports · 2018 · 130 citations
    3. Human epidermal neural crest stem cells as a source of Schwann cells Development · 2015 · 44 citations
    4. The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells Cell proliferation · 2023 · 5 citations
    5. Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling Burns & Trauma · 2025 · 1 citations
    6. 0867 The role of schwann cell - macrophage interactions in keloid pathogenesis Journal of Investigative Dermatology · 2025
    7. <i>PIK3CA</i> gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect Proceedings of the National Academy of Sciences · 2025
    8. Keratin Biomaterials Activate Schwann Cells via Integrin‐Mediated Signaling and Promote Regeneration of Large Peripheral Nerve Defects in a Rabbit Model The FASEB Journal · 2009
    9. Sexually dimorphic effect of progesterone and its reduced metabolites on the gene expression of myelin proteins in rat Schwann cells Frontiers in Neuroendocrinology · 2006
    10. Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage bioRxiv (Cold Spring Harbor Laboratory) · 2020
    11. Human Hair Derived Keratins Mediate Schwann Cell Behavior in vitro and Facilitate Rapid Peripheral Nerve Regeneration in vivo ˜The œFASEB journal · 2007
    12. Pluripotent Hair Follicle Neural Crest Stem-Cell-Derived Neurons and Schwann Cells Functionally Repair Sciatic Nerves in Rats Molecular Neurobiology · 2009 · 36 citations
    13. Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination Nature Neuroscience · 2016 · 133 citations
    14. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function Cell Cycle · 2008 · 144 citations
    15. Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral‐nerve injury: An advantageous alternative to ES and iPS cells Journal of Cellular Biochemistry · 2009 · 121 citations
    16. Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins Stem cells · 2010 · 106 citations
    17. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    18. Nestin‐positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury The Journal of Dermatology · 2011 · 57 citations
    19. Multipotent nestin‐expressing hair follicle stem cells The Journal of Dermatology · 2009 · 37 citations
    20. The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine Journal of Dermatological Science · 2010 · 33 citations
    21. Induction of Skin-Derived Precursor Cells from Human Induced Pluripotent Stem Cells PLOS ONE · 2016 · 21 citations
    22. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance 2019 · 11 citations
    23. Epidermal Stem Cells in Orthopaedic Regenerative Medicine International journal of molecular sciences · 2013 · 3 citations
    24. Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin Elsevier eBooks · 2018 · 1 citations
    25. The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell Springer eBooks · 2008 · 1 citations
    26. Hair-follicle-associated pluripotent (HAP) stem cells Journal of dermatological science · 2016
    27. Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation 2018
    28. The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves Biomaterials · 2007 · 309 citations
    29. The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles eLife · 2014 · 106 citations
    30. The effect of human hair keratin hydrogel on early cellular response to sciatic nerve injury in a rat model Biomaterials · 2013 · 105 citations