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120-150 / 1000+ resultsresearch The Comparative Potency of Hydrocortisone Analogs in Suppressing Growth of Hair in the Rat121From the Departments of Dermatology and Syphilology and of Anatomy, University of Michigan Medical School, Ann Arbor, Michigan.2Supported in part by research grants from the National Institutes of Health, United States Public Health Service (A-131 (C5)), the University of Michigan Memorial-Phoenix Project #145 and The Upjohn Company.
9α-21-difluoro-21-desoxyhydrocortisone is the most effective at stopping hair growth in rats.
research A Pre-Experimental Study to Assess the Effectiveness of Structured Teaching Program on Knowledge regarding Polycystic Ovary Syndrome among Adolescent Girls studying in selected Senior Secondary School, Amritsar, Punjab
This study found that a structured teaching program significantly improved adolescent girls' knowledge of polycystic ovary syndrome.
research SUMMARY OF CONTACT WITH DR. MARIK. PULMONARY MEDICINE AND CRITICAL CARE. EASTERN VIRGINIA MEDICAL SCHOOL - USA.
In this note, editors discuss the reproduction of medical content by Dr. Paul E. Marik, related to standardized coronavirus treatments, emphasizing that the materials appear effective and cautioning readers to consult their doctors for guidance.
research Alopecia Areata: Pituitary Function Assessed by Assay of Pituitary Gonadotropin in Urine11From the Section of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota. The Mayo Foundation, Rochester, Minnesota, is a part of the Graduate School of the University of Minnesota.
research The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves
This study found that a biomaterial gel made from human hair keratins facilitated nerve regeneration in an animal model, potentially matching the effectiveness of traditional autografts.
research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes
This study found that previously undescribed WNT10A mutations are a prominent cause of various forms of ectodermal dysplasia, including OODD and Schöpf-Schulz-Passarge syndrome, with gender-specific phenotypic effects noted.
research Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function
This study found that in mice, transplanting hair follicle stem cells promoted recovery from spinal cord injury, as these cells largely differentiated into Schwann cells aiding nerve repair.
research Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral‐nerve injury: An advantageous alternative to ES and iPS cells
In this study, human hair follicle pluripotent stem cells transplanted into severed mouse sciatic nerves differentiated into Schwann cells and supported nerve regeneration, offering a promising alternative to embryonic or iPS cells for regenerative medicine.
research The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles
This study concluded that terminal Schwann cells are essential for the maintenance and regeneration of mechanosensory lanceolate complexes at hair follicles in adult mice.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
This study found that skin-derived precursor cells in mice can originate from both neural crest and somite lineages but show functional similarities regardless of their developmental origins.
research The effect of human hair keratin hydrogel on early cellular response to sciatic nerve injury in a rat model
In this study, the researchers found that a keratin hydrogel filler in nerve conduits led to earlier Schwann cell migration and improved cellular behaviors compared to other fillers in a rat sciatic nerve model.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
This review discusses strategies for regenerating cutaneous nerve function in burn patients and highlights the potential role of autologous skin-derived adult stem cells in improving sensory recovery, but reports no new experimental findings.
research Diversification and Specialization of Touch Receptors in Skin
This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.
research Regeneration of skin appendages and nerves: current status and further challenges
This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
This review discusses melanocyte development, emphasizing the plasticity of melanoblasts and the role of both intrinsic and extracellular signals in their differentiation and migration, with no new clinical results reported.
research Nestin‐positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury
This study found that transplanting human hair follicle pluripotent stem cells can promote the recovery of sciatic nerve function in a mouse model of nerve impingement.
research Multipotent nestin‐expressing hair follicle stem cells
In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.
research Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model
This study demonstrated that keratin derived from human hair can improve axon extension and alleviate motor deficits from sciatic nerve injuries, highlighting its potential as a promising biomaterial for peripheral nerve regeneration.
research De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
This study found genetic variations, including de novo variants and copy number variations, that may be associated with phenotypic discordance in monozygotic twins with various clinical conditions.
research Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation
This study observed that dietary intake of glucoraphanin during juvenile and adolescent stages prevented cognitive deficits and abnormal gene expressions in the brain of adult offspring exposed to maternal immune activation, potentially implicating centrosome-related genes in the development of psychosis.
research Periorbital facial rejuvenation; applied anatomy and pre-operative assessment
This review highlights essential preoperative assessments for ophthalmologists and non-oculo-facial surgeons performing upper facial rejuvenation, emphasizing the importance of understanding ocular and periocular anatomy to achieve both cosmetic and functional improvements.
research Three-dimensional microanatomy of longitudinal lanceolate endings in rat vibrissae
This study re-examined the structure of lanceolate endings in rat vibrissae, suggesting that their apical cones may function as a transducer site for detecting hair movements.
research The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine
This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.
research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids
This article discusses the functions of the enzyme 17beta-HSD10, including its role in steroid metabolism and potential links to Alzheimer's disease, but reports no new experimental findings.
research Induction of Skin-Derived Precursor Cells from Human Induced Pluripotent Stem Cells
This study developed a new protocol to efficiently produce skin dermal stem cells from human induced pluripotent stem cells, which may aid in treating various skin disorders.
research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.
research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls
This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.
research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance
This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.
research Subclinical hypothyroidism does not influence the metabolic and hormonal profile of women with PCOS
This study found that subclinical hypothyroidism had minimal impact on the metabolic and hormonal profiles of women with polycystic ovary syndrome.