97 citations
,
January 1999 in “International Journal of Dermatology” Pityriasis rubra pilaris is a rare skin disorder with reddish-orange patches and thickened skin, needing better treatment understanding.
81 citations
,
February 2000 in “Anti-cancer drugs” In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
71 citations
,
November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This article discusses the complexities of diagnosing and managing polycystic ovary syndrome in adolescents and highlights the lack of established diagnostic criteria and unclear clinical implications, without presenting new clinical findings.
65 citations
,
November 2019 in “European Journal of Pharmacology” This review discusses the role of anti-androgen therapies in cancer and other diseases and reports no new clinical results, highlighting both old and new generations of anti-androgens.
65 citations
,
January 2005 in “American journal of clinical dermatology” This article reviews the diagnosis and treatment of tinea capitis in children, noting that newer antifungal agents can offer effective systemic therapy alongside supportive topical treatments; it reports no new clinical findings.
61 citations
,
October 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses scalp skin disorders, their overlapping symptoms, diagnostic techniques, and treatment strategies, emphasizing the importance of accurate differential diagnosis, but reports no new clinical results.
59 citations
,
October 1976 in “Acta Neurologica Scandinavica” This study found that sodium valproate significantly reduced seizure frequency by over 50% in about 70% of patients with generalized seizures but was less effective for partial seizures.
50 citations
,
February 2007 in “Expert Opinion on Biological Therapy” This study found that hair follicle stem cells can effectively enhance nerve regeneration and restore function in peripheral nerve injuries in mice, suggesting their potential as a source for autologous stem cell therapy.
49 citations
,
September 2015 in “Psychoneuroendocrinology” This study suggests that the 5α-reductase inhibitor finasteride modulates sensorimotor gating in rats by affecting D1 and D3 receptors, but not D2 receptors, with varying effects based on genetic strain.
45 citations
,
November 2005 in “Journal of pediatric health care” This review discusses pediculosis capitis, emphasizing its diagnosis and treatment strategies, but reports no new clinical results; the authors highlight the need for concurrent treatment of all close contacts.
43 citations
,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” This paper reviews symptoms, causes, and treatment strategies for common scalp conditions such as dandruff and psoriasis, but does not present new clinical findings.
42 citations
,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
37 citations
,
May 2018 in “Developmental Biology” This review discusses the role of neural crest stem cell-like states in adult neural crest-derived tissues, suggesting they may contribute to tissue repair by generating new cell types and activating repair programs.
36 citations
,
January 2012 in “International Journal of Trichology” This review discusses madarosis, its diverse causes, and suggests follicular unit transplantation as a useful treatment for scarring types, but reports no new clinical results.
35 citations
,
November 2020 in “Experimental Dermatology” This study found that upper wound fibroblasts are crucial for hair follicle regeneration during wound healing and suggests that these cells, along with papillary fibroblasts, migrate within the wound.
35 citations
,
June 1997 in “Annals of the New York Academy of Sciences” Early diagnosis and multidisciplinary care are crucial for managing PCOS in adolescents.
34 citations
,
February 2018 in “Drug Design Development and Therapy” This source reports that bimatoprost, a medication approved for eyelash growth, has shown efficacy in treating eyebrow hypotrichosis, suggesting it as a noninvasive, effective, and well-tolerated option for enhancing eyebrow hair.
34 citations
,
December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
32 citations
,
June 2017 in “Journal of infection/The Journal of infection” This source discusses the diagnosis and treatment of Tinea capitis in children, highlighting that Trichophyton tonsurans is the prevalent cause in the UK and that terbinafine is an effective treatment option.
32 citations
,
April 2015 in “British Journal of Dermatology” This article discusses hair shedding in women and does not offer new research results; it highlights the need for objective criteria to define excessive hair shedding.
30 citations
,
September 2020 in “Journal of Patient-Reported Outcomes” This study found that alopecia areata significantly impacts emotional and psychological well-being, relationships, and lifestyles, highlighting the need for increased awareness and effective treatments.
28 citations
,
January 2015 in “Skin appendage disorders” This study examined children with trichotillomania using a set of specific questions to better understand the condition and aid clinicians who may be unfamiliar with it.
27 citations
,
January 1990 in “Child Psychiatry & Human Development” This review discusses the demographic, dermatologic, clinical, and psychodynamic aspects of trichotillomania, exploring its potential link to anxiety but reports no new clinical findings.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
22 citations
,
November 2005 in “BMC Cancer” This phase II study found that gemcitabine plus paclitaxel showed promising activity and manageable toxicity as first-line therapy for recurrent or metastatic breast cancer, with a 35% overall response rate.
21 citations
,
September 2013 in “Journal of circadian rhythms” In this study, heavy nighttime physical exercise delayed the circadian phase of clock gene expression by 2 to 4 hours in a professional fighter, suggesting potential implications for managing circadian disorders.
21 citations
,
June 2002 in “International Journal of Cosmetic Science” Advancements in hair keratin research could lead to better hair health treatments.
17 citations
,
May 2007 in “British Journal of Dermatology” This case report describes a child with Gomez–Lopez–Hernandez syndrome, highlighting developmental challenges and medical interventions, yet noting academic success and participation in mainstream activities.
17 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
15 citations
,
February 2019 in “Internal Medicine Journal” This study found that experienced Australian prescribers of hormone therapy for transgender adults often follow international guidelines but highlight the need for better training and specific local guidelines.