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Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

The letter criticizes generalizations about older patients' abilities and calls for respectful, individualized care, while the original authors defend the need to adapt communication for those with impairments.

Finasteride and SSRIs together increase impotence and low libido risk in men.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Different types of skin cells play specific roles in development, healing, and cancer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Estrogen therapy can reduce skin aging but has cancer risks.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.