research Quantification of the Vitamin D Receptor-Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
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360-390 / 547 resultsresearch Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Depositing Alpha-Mangostin Nanoparticles to Sebaceous Gland Area for Acne Treatment
α-mangostin nanoparticles improved acne with minimal irritation.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research Smart Microneedles for Therapy and Diagnosis
Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
research Alopecia: A Review of Laser and Light Therapies
Lasers might help hair growth in some alopecia cases, but more research is needed to confirm their effectiveness and safety.
research Effect of Shampoo, Conditioner, and Permanent Waving on the Molecular Structure of Human Hair
Perming significantly changes hair's molecular structure, while shampoo and conditioner do not.
research Polymer Conjugated Retinoids for Controlled Transdermal Delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
research Current Advances of Nanocarrier Technology-Based Active Cosmetic Ingredients for Beauty Applications
Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Novel Approaches to Characterize Age-Related Remodeling of the Dermal-Epidermal Junction in 2D, 3D, and In Vivo
3D imaging shows clearer details of skin structure changes with age.
research Nanoethosomes for Dermal Delivery of Lidocaine
Nanoethosomes can improve the skin penetration of Lidocaine for topical use.
research Synthesis and Validation of Functional Nanogels as pH-Sensors in the Hair Follicle
Scientists created tiny pH-sensing gels that can safely measure the pH levels inside hair follicles.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research Quaternary Ammonium Iminofullerenes Improve Root Growth of Oxidative-Stress Maize Through ASA-GSH Cycle Modulating Redox Homeostasis of Roots and ROS-Mediated Root-Hair Elongation
Quaternary ammonium iminofullerenes help maize roots grow better under stress by reducing oxidative damage.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
research Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential
Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance
Hair lipids do not protect against humidity.
research Targeted Delivery of Zinc Pyrithione to Skin Epithelia
Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
research Optical Studies of Nanodiamond-Tissue Interaction: Skin Penetration and Localization
Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
research Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions
Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
research Highlighting Nuances of Blue Light Phototherapy: Mechanisms and Safety Considerations
Blue light therapy is safe for skin and may protect against UV radiation.
research Physicochemical Characterization of Finasteride Nanosystem for Enhanced Topical Delivery
Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.
research Unique Hair Properties That Emerge from Combinations of Multiple Races
Mixed-race individuals have hair with varied shapes and more root damage.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research A Quantitative Technique to Analyze and Evaluate Microstructures of Skin Hair Follicles Based on Mueller Matrix Polarimetry
The technique accurately identifies and evaluates hair follicle structures in skin.
research Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel from Human Hair-Derived Keratin Microparticle Carriers
Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
research Classification of Male-Pattern Hair Loss
No current system perfectly classifies male-pattern hair loss, indicating a need for a new system for better diagnosis and treatment.