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    Glossary Scarless Wound Healing

    process where tissue repairs without forming a scar

    Scarless wound healing refers to the process by which the body repairs tissue damage without forming a scar. This type of healing is typically seen in fetal development and involves a complex interplay of cellular and molecular mechanisms that promote tissue regeneration rather than fibrosis. For professionals, it is of particular interest because understanding these mechanisms could lead to advanced treatments for improving wound healing in adults.

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    Research 30 of 495

    1. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    2. Toward understanding scarless skin wound healing and pathological scarring F1000Research · 2019 · 113 citations
    3. Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles Advanced Healthcare Materials · 2020 · 89 citations
    4. Scarless wound healing: Transitioning from fetal research to regenerative healing Wiley Interdisciplinary Reviews-Developmental Biology · 2018 · 79 citations
    5. Engineering Pro‐Regenerative Hydrogels for Scarless Wound Healing Advanced Healthcare Materials · 2018 · 55 citations
    6. Pro‐Regenerative Hydrogel Restores Scarless Skin during Cutaneous Wound Healing Advanced Healthcare Materials · 2017 · 41 citations
    7. Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration Military Medical Research · 2024 · 37 citations
    8. Novel Biodegradable Polymeric Microparticles Facilitate Scarless Wound Healing by Promoting Re-epithelialization and Inhibiting Fibrosis Frontiers in Immunology · 2018 · 37 citations
    9. Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing Journal of Investigative Dermatology · 2007 · 21 citations
    10. Scarless wound healing – a literature review Romanian Journal of Pediatrics · 2019 · 2 citations
    11. An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing RSC Advances · 2026
    12. Senescence-induced reparative fibroblasts enable scarless wound healing in aged murine skin. bioRxiv (Cold Spring Harbor Laboratory) · 2025
    13. Temperature‐sensitive hydrogel releasing pectolinarin facilitate scarless wound healing Journal of Cellular and Molecular Medicine · 2024
    14. Skin wounds in the MRL/MPJ mouse heal with scar Wound Repair and Regeneration · 2006 · 51 citations
    15. A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus Frontiers in Cell and Developmental Biology · 2021 · 42 citations
    16. Dermal Fibrosis and the Current Scope of Hydrogel Strategies for Scarless Wound Healing Fibrosis · 2024 · 1 citations
    17. Bioadhesive Polydopamine-Vitamin A Derivative Hydrogels Reprogram the Wound Microenvironment for Scarless Wound Healing and Hair Follicle Regeneration Materials Horizons · 2026
    18. 977 The wound healing of fractional photothermolysis mimicks scarless healing with minimal myofibroblast activation Journal of Investigative Dermatology · 2019
    19. An In Vivo Mouse Excisional Wound Model of Scarless Healing Plastic and Reconstructive Surgery · 2006 · 58 citations
    20. Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound Healing Advanced materials · 2023 · 8 citations
    21. In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing bioRxiv (Cold Spring Harbor Laboratory) · 2024
    22. New insights into balancing wound healing and scarless skin repair Journal of Tissue Engineering · 2023 · 108 citations
    23. A study of scarless wound healing through programmed inflammation, proliferation and maturation using a redox balancing nanogel Journal of Biomedical Materials Research Part A · 2024 · 3 citations
    24. Sprayable biomimetic double mask with rapid autophasing and hierarchical programming for scarless wound healing Science Advances · 2024 · 47 citations
    25. Accelerated, injectable, self-healing, scarless wound dressings using rGO reinforced dextran/chitosan hydrogels incorporated with PDA-loaded asiaticoside International Journal of Biological Macromolecules · 2024 · 17 citations
    26. In-vitro and In-vivo Characterization of Bio-Patch to Hydrogel on Skin Wounds for Efficient Scarless Wound Healing Journal of chemical health risks · 2024
    27. MSC-derived sEV-loaded hyaluronan hydrogel promotes scarless skin healing by immunomodulation in a large skin wound model Biomedical Materials · 2022 · 39 citations
    28. Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing ACS Applied Materials & Interfaces · 2023 · 7 citations
    29. A bioactive, multifunctional hydrogel dressing from sugarcane molasses extract promotes scarless healing in chronic wounds via microenvironment-responsive drug release Chemical Engineering Journal · 2026
    30. Cutaneous wound healing: recruiting developmental pathways for regeneration Cellular and Molecular Life Sciences · 2012 · 471 citations