18 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
25 citations
,
September 2014 in “Dermatologic Surgery” This study found that hair transplantation using round grafts improved hair growth in African American women with end-stage CCCA, showing no postoperative scarring in the donor or recipient areas.
2 citations
,
November 2023 in “International Journal for Research in Applied Science and Engineering Technology” This review explores various tissue regeneration technologies, highlighting how skin substitutes have significantly improved healing success rates for burn injuries, and examines cell-based therapies aimed at reducing scar formation and improving burn management.
1 citations
,
December 2011 in “Journal of The American Academy of Dermatology” This book review examines various classification and treatment methods for acne scars, emphasizing the complexity and need for multiple therapeutic approaches, but reports no new clinical results.
60 citations
,
June 2019 in “Ageing Research Reviews” This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.
24 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses potential complications in surgical hair restoration and emphasizes the importance of both patient and physician actions in minimizing these risks; it reports no new results.
9 citations
,
March 2020 in “Dermatologic Surgery” This study found that both FUE and FUT methods are equally effective in producing high-quality hair grafts, with FUE offering the advantage of less noticeable scarring compared to FUT.
6 citations
,
January 2023 in “npj regenerative medicine” This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.
1 citations
,
October 2025 in “International Journal of Nanomedicine” This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.
113 citations
,
July 2015 in “Journal of Cosmetic Dermatology” This review discusses the cosmetic applications of platelet-rich plasma in dermatology, highlighting its potential benefits and the need for more controlled studies.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” This review discusses various techniques for evaluating hair shedding and alopecia but reports no new clinical results. The authors emphasize the value of specific clinical and instrumental methods in assessing hair growth.
22 citations
,
August 2010 in “Annals of Plastic Surgery” This study suggests that reconstructive methods for burn alopecia should be tailored to the conditions of the scarring, with scalp extension and expansion recommended only for large, poor-quality alopecia due to a high complication rate.
13 citations
,
April 2025 in “International Journal of Nanomedicine” In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.
12 citations
,
April 2014 in “Facial Plastic Surgery Clinics of North America” This review evaluates neck rejuvenation techniques, including cervical rhytidectomy, and discusses potential surgical complications, without presenting new clinical findings.
11 citations
,
January 2016 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This study reported that direct brow lift surgery provided excellent and long-lasting results in bald men with high anterior hairlines, despite visibility of the scar in a few cases.
9 citations
,
November 2008 in “Facial Plastic Surgery” This article reviews techniques for repairing scalp deformities and concludes that combining older methods with modern hair restoration allows for satisfactory treatment of large scarred areas.
8 citations
,
January 2021 in “Smart materials in medicine” This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.
5 citations
,
August 2022 in “Mediators of Inflammation” This study found that combining pulsed dye laser with pingyangmycin improved treatment efficacy, scar repair, skin condition, and patient satisfaction in treating post-acne hyperplastic scars, compared to laser alone, without increasing adverse reactions.
June 2022 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study found that autologous emulsified fat followed by hair transplantation using FUE was more effective than FUE alone in improving outcomes for patients with cicatricial alopecia after six months.
June 2004 in “Dermatologic Surgery” The commentary suggests that using a single-scar technique for hair transplants can give good cosmetic results, but some surgeons hesitate to use it despite ways to address their concerns.
July 2020 in “Journal of Cosmetic and Laser Therapy” This study found that platelet-rich plasma injections significantly increased hair density and width while improving patient satisfaction in androgenic alopecia treatment without adverse effects.
7 citations
,
September 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” In this randomized controlled trial, occipital donor sites for split-thickness skin grafts showed superior re-epithelialization, reduced pain, fewer complications, and better cosmetic outcomes compared to femoral donor sites.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.
168 citations
,
August 2000 in “American Journal of Pathology” This study suggests that fibromodulin may regulate transforming growth factor-β activity during scar formation, influencing the transition from fetal scarless repair to adult scar-forming repair in rats.
48 citations
,
March 2019 in “Frontiers in Physiology” This review discusses the typical wound healing process in skin and the oral cavity, and emphasizes the research focus on achieving scarless healing in adult skin, but reports no new clinical results.
32 citations
,
March 2014 in “PLOS ONE” This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.
10 citations
,
July 2011 in “Wound Repair and Regeneration” This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.
8 citations
,
January 1986 in “The Journal of Dermatologic Surgery and Oncology” This article discusses surgical treatments for male pattern hair loss in black individuals, emphasizing the need for technique adjustments due to specific characteristics of black skin and hair, but reports no new clinical results.
7 citations
,
March 2014 in “ISRN Biomaterials” In this study, a keratin hydrogel improved survival rates and functional recovery in rats with spinal cord injuries, suggesting potential for SCI treatment that merits further investigation.
5 citations
,
April 2024 in “BMJ Open” This scoping review revealed that methods for measuring traumatic scar thickness using ultrasound are inconsistently reported and mainly remain in early research phases, highlighting a need for standardizing these methods to bridge the gap to routine clinical practice.