November 2024 in “The Journal of Cell Biology” This study revealed that basement membrane dynamics are crucial to hair follicle development, influencing progenitor cell behavior and cell division patterns in developing mouse hair follicles.
May 2024 in “International journal of molecular sciences” This review synthesizes evidence on platelet-derived bioproducts like PRP and PRF, highlighting their role in tissue regeneration and their benefits in aesthetic medicine applications such as hair restoration, scar treatment, and wound healing.
April 2021 in “Journal of Investigative Dermatology” This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.
March 2018 in “Dermatología Argentina” This study found that postmenopausal women in Argentina with frontal fibrosing alopecia had a higher average age of diagnosis than previously reported, with similar clinical features to international cases.
January 2016 in “Springer eBooks” The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
This article provides no abstract or new findings and focuses on a patient registry related to spasticity care.
May 2026 in “European Burn Journal” This systematic review concluded that the scalp can be a safe and effective donor site for split-thickness skin grafts in pediatric burn patients, with evidence indicating good scar quality and manageable complications, though a rigorous technique is essential to minimize risks.
October 2025 in “International Wound Journal” In a study using a rat model of hypertrophic scars, researchers found that gamma-irradiated human amniotic fluid improved wound healing, collagen remodelling, immune response, and scar characteristics more effectively than saline or non-irradiated amniotic fluid, indicating its potential for clinical applications in scar management.
January 2025 in “Advances in Clinical Medicine” This source highlights that fractional CO2 laser, as a minimally invasive technology, shows significant benefits in treating various skin and mucosal conditions by improving therapeutic outcomes, shortening recovery times, and enhancing precise personalized interventions through emerging technologies like AI and biomarker monitoring.
July 2023 in “Bioengineering & translational medicine” This study explored a cell-free therapy with mesenchymal stem cell paracrine proteins and PEG hydrogels for deep burn treatment and found that the combination significantly enhanced wound healing, reduced scar formation, and promoted skin appendage regeneration in a rabbit model.
275 citations
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March 1999 in “Journal of The American Academy of Dermatology” This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.
243 citations
,
September 2016 in “Dermatology and Therapy” This article provides an overview of how dermoscopy can aid in the noninvasive diagnosis of various general dermatological disorders, grouped by clinical presentation, but reports no new clinical results.
176 citations
,
January 2003 in “Journal of Investigative Dermatology” This review summarizes the roles of bone morphogenetic proteins in the development and regulation of normal and diseased skin, but it does not provide new clinical results.
152 citations
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March 1988 in “Journal of The American Academy of Dermatology” In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.
86 citations
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August 2014 in “Journal of The American Academy of Dermatology” This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.
85 citations
,
December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
68 citations
,
August 2014 in “Stem Cells Translational Medicine” This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.
54 citations
,
June 1990 in “Journal of The American Academy of Dermatology” This review discusses various skin infections and conditions that commonly occur in patients with HIV, but it does not report new research findings.
53 citations
,
April 2021 in “Cell Host & Microbe” This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.
41 citations
,
September 2005 in “Wound Repair and Regeneration” This study found that hydrogen peroxide interfered with scarless healing in a murine fetal wound repair model, potentially by inducing transforming growth factor-beta1, which may contribute to increased fibrosis.
37 citations
,
February 2019 in “Experimental Dermatology” This study explored the regenerative abilities of the African spiny mouse's skin, revealing more robust wound-induced hair follicle neogenesis compared to laboratory mice and highlighting unique features of its hair and wound response.
33 citations
,
January 1991 in “The Journal of Dermatologic Surgery and Oncology” This article describes incisional slit grafting as an improved hair transplantation method, using smaller grafts and conserving vascular supply to enhance graft yield and achieve a more natural hairline, but reports no new research results.
31 citations
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November 2013 in “Dermatologic Clinics” This article discusses the use of a robotic system for hair graft harvesting in hair restoration surgery, focusing on its capabilities and the advantages and disadvantages, but it reports no new clinical findings.
30 citations
,
December 2017 in “Medical Hypotheses” This review evaluates dihydrotestosterone's role in androgenic alopecia and proposes a model suggesting that chronic scalp tension and inflammation contribute to hair follicle miniaturization, identifying fibrosis, calcification, and tension as treatment targets.
23 citations
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March 2001 in “Clinics in dermatology” This study found that 363 genes were differentially expressed in alopecia areata skin compared to non-lesional skin, suggesting T-cell mediated immune responses and distinct gene profiles related to the disease's stage.
21 citations
,
March 2019 in “Journal of The American Academy of Dermatology” This review discusses the dermatologic care of transgender individuals and highlights the need for more quantitative research to improve clinical understanding and support future studies.
20 citations
,
May 2016 in “Journal of Cutaneous Pathology” This study suggests that the presence and arrangement of plasmacytoid dendritic cells can help distinguish chronic cutaneous lupus erythematosus from other types of scarring alopecia.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
13 citations
,
July 2004 in “Skinmed” This article reviews the structure and function of hair follicles, diagnostic approaches, and treatments for nonscarring alopecias, but reports no new clinical results.
11 citations
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January 2007 in “Aesthetic Plastic Surgery” This study found that follicular unit transplantation effectively corrected postrhytidoplasty stigmas like visible scars or displaced hairlines, with high patient satisfaction and a low complication rate.