February 2024 in “Frontiers in physiology” This study examines the role of hair follicle stem cells in epidermal regeneration during skin soft tissue expansion, proposing a potential method for their cellular and molecular regulation.
11 citations
,
February 2019 in “Stem cells international” In this study, researchers found that while both hair follicles and skin dermis-derived neural crest stem cells are suitable for large-scale manufacturing, skin dermis cells grow faster and are easier to obtain.
1 citations
,
January 2010 This article reviews various reconstruction techniques for scalp alopecia, highlighting the challenges of applying traditional flap methods and the limitations of hair grafting on unstable scars but offers no new study results.
1 citations
,
January 1993 in “Facial Plastic Surgery” Surgical hair restoration has improved since 1959, with new techniques like minigrafts, micrografts, and scalp reductions creating more natural hairlines and reducing bald skin, despite some risks and potential for scarring.
April 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” This study concluded that both follicular unit extraction and scalp expanders are effective for hair restoration in secondary cicatricial alopecia when tailored to patient-specific factors.
January 2022 in “Plastic and Aesthetic Research” This review explores techniques for scalp reconstruction, focusing on local flap design and execution, without reporting new clinical findings.
28 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a serious complication of follicular unit extraction, where donor-site necrosis led to cicatricial alopecia, but was successfully treated with two-stage surgery using tissue expanders.
In this retrospective analysis, researchers evaluated 54 patients undergoing soft tissue reconstruction for scalp and forehead defects and reported excellent aesthetic outcomes with local flaps for defects up to 50 cm², while larger defects typically required additional skin grafting.
1 citations
,
October 2018 in “InTech eBooks” This article reviews treatment approaches for cicatricial alopecia, describing how medication efficacy varies and suggesting autologous hair transplantation for stable cases; no new clinical data are presented.
12 citations
,
May 1989 in “Postgraduate Medicine” This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.
May 2026 in “The EMBO Journal” This study demonstrated how cellular flows and tissue mechanics guide the topological transformations in avian skin, essential for feather follicle development from scales.
126 citations
,
January 1987 in “Journal of The American Academy of Dermatology” This article reviews the classification of hair shaft abnormalities, outlining their diagnostic features, but does not present new research findings.
1 citations
,
November 2002 in “Neurosurgery Clinics of North America” This article reviews the role of androgens in male pattern hair loss and its emotional impact, but reports no new clinical findings.
7 citations
,
April 2015 in “Plastic and Aesthetic Nursing” This article reviews the causes of hair loss and explores various options for restoring the hairline, but reports no new clinical results.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
3 citations
,
August 2011 in “InTech eBooks” This article discusses the applications and contraindications of skin grafts in wound treatment and reports no new research findings.
January 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This article discusses beard reconstruction techniques focusing on surgical algorithms and the use of tissue expansion, reporting no new clinical results.
11 citations
,
September 2013 in “Otolaryngologic Clinics of North America” This review outlines various techniques to improve facial scars following trauma but reports no new clinical results, highlighting the need for further research to address psychosocial impacts.
December 2002 in “Operative Techniques in Otolaryngology-Head and Neck Surgery” This article reviews special techniques for reconstructing the appearance of patients with scalp injuries, highlighting the versatility of scalp expansion, advancement flaps, and follicular unit hair transplantation, and reports no new clinical results.
5 citations
,
July 2018 in “Experimental Dermatology” In this study, researchers developed a relatively simple punch assay for regenerating hair follicles using mouse or human cells, finding efficient hair formation with mouse cells but low efficiency with human cells on reconstituted human skin.
1 citations
,
November 2018 in “immuneACCESS” This study found that in alopecia areata, treatment with the oral JAK-inhibitor tofacitinib decreased clonally expanded CD8⁺ T cells in the scalp, but many expanded clones did not completely disappear, potentially leading to relapse after stopping treatment.
January 2024 in “ACS Biomaterials Science & Engineering” In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.
3 citations
,
September 2013 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using ex vivo dermatoscopy can improve the accuracy of scalp biopsy processing by correctly guiding tissue bisection and potentially reducing laboratory costs and turnaround time.
This study revealed that during avian skin development, complex tissue architecture results from specific cellular flows and mechanical processes that guide feather bud protrusion and elongation, with distinct differences noted in scale development, where rigidity restricts such transformations.
140 citations
,
December 2017 in “Journal of Controlled Release” This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
1 citations
,
November 2023 in “Indian Journal of Dermatology” This case report documents the first known instance of congenital lipedematous alopecia in a male, specifically a 6-year-old Asian boy, characterized by scalp thickening and sparse hair growth without inflammation, and highlights the need for further research to understand its pathogenesis and treatment.
November 2025 in “Communications Materials” This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.
1 citations
,
February 2025 in “International Journal of Molecular Sciences” This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.
1 citations
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July 2023 in “Journal of Cutaneous and Aesthetic Surgery” This review highlights the advantages of a new "Multi-Wave Punch" for follicular unit extraction in hair transplantation, noting its design reduces follicular damage and improves graft quality by effectively separating hair follicles from surrounding tissue.
September 2016 in “Journal of dermatological science” This study found that adult dermal papilla cells guided high-passage adult keratinocytes to produce new hair fibers, suggesting potential for large-scale hair follicle bioengineering.