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Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

RANK-RANKL signaling is essential for hair growth and skin health.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Hydrogels could lead to better treatments for wound healing without scars.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Melatonin may reduce skin damage caused by X-rays in rats.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

The new skin patch with human matrix and antibiotic improves wound healing.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.