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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.

Jaw wiring helps with weight loss but long-term habits are needed to keep it off.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.

Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

MAFT is a reliable method for forehead contouring with high patient satisfaction and long-term results.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.