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Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Fullerenes show potential in skin care but need more safety research.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Liposomes better deliver minoxidil for hair loss treatment than niosomes.

Treatments for melanin disorders exist, but more effective options needed.

Hair follicle regeneration needs special conditions and young cells.

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.

PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.

HIV can cause unusual and severe skin problems that are hard to treat.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.