research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
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research Theoretical Considerations in Laser Hair Removal
Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
research Transdermal Permeation of Drugs in Various Animal Species
Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Vitamin D and the Skin: Focus on a Complex Relationship
Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis
Tofacitinib may help treat severe hair loss, but more research is needed.
research Obesity and the Skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research Probiotic Bacteria Induce a Glow of Health
Probiotic bacteria improved skin and hair health in aged mice.
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research Terbinafine Levels in Serum, Stratum Corneum, Dermis-Epidermis, Hair, Sebum, and Eccrine Sweat
Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Platelet-Rich Plasma in Dermatology: Boon or Bane?
Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
research Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered
The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
research Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses
Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
research Male-Pattern Baldness Susceptibility Locus at 20p11
Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
Activating TRPV3 stops human hair growth.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Preparation and Characterization of Minoxidil Loaded Nanostructured Lipid Carrier Gel for Effective Treatment of Alopecia
Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.
research Fullerene Nanoparticles in Dermatological and Cosmetic Applications
Fullerenes show potential in skin care but need more safety research.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Male Androgenetic Alopecia
Hair loss in men treated best with early medication or transplant, new treatments researched.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.