2 citations
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October 2021 in “JID innovations” This study found no significant gene expression differences in the lesional scalp of patients with central centrifugal cicatricial alopecia with and without a history of uterine leiomyomas.
September 2023 in “Journal of the American Academy of Dermatology” This study, examining perceptible hair density changes in androgenetic alopecia patients, found that dermatologists could accurately detect hair loss at a lower threshold than previously noted, specifically at a 22.66% relative density difference, challenging assumptions about their predictive accuracy based solely on clinical examination.
32 citations
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March 2016 in “American Journal of Physical Anthropology” This study suggests that chemical methods can reveal subtle differences in scalp hair color variability across populations and emphasizes the need for enhanced understanding of hair fiber curvature.
28 citations
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March 1973 in “The Journal of Clinical Endocrinology & Metabolism” This study found that hair follicles from balding men show significant metabolic differences compared to those from non-balding individuals, particularly in their ability to process dehydroepiandrosterone.
8 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.
24 citations
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September 2012 in “Dermatologic Surgery” The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.
March 2026 in “International Journal of Dermatology” In this study, researchers observed that patients with androgenetic alopecia show differences in scalp microbial communities compared to the general population, including an increase in Cutibacterium acnes, particularly in males, which may interact with lipid and immune pathways to contribute to hair follicle miniaturization.
January 2023 in “Indian Dermatology Online Journal” This study found that there was no significant difference in hair regrowth between clobetasol and bimatoprost for scalp alopecia areata over 12 weeks, but bimatoprost had fewer side effects and prompted earlier, more pigmented hair regrowth.
17 citations
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October 2003 in “Brazilian Journal of Medical and Biological Research” This study found that SDR5A1 gene expression was similar between hirsute women, normal women, and men, suggesting it may not explain differences in hair growth among these groups.
11 citations
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August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
5 citations
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January 1976 in “Acta Dermato Venereologica” This study found that sodium and potassium hair levels may serve as sex-specific indicators, with slight differences in copper and iron content between males and females, particularly during the female reproductive period.
2 citations
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February 2021 in “European Journal of Plastic Surgery” This study found that the Fibonacci 'snail' flap for scalp defect reconstruction healed faster and resulted in better aesthetic outcomes than skin grafts, though not all complication rate differences were statistically significant.
2 citations
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April 2020 in “Clinical and experimental obstetrics & gynecology” This study measured estradiol and progesterone in the scalp hair of pre- and postmenopausal women using immunoassay, but found no statistical significance in hormone concentration differences between the groups.
1 citations
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January 1997 in “Skin Pharmacology and Physiology” In this study, researchers found a significant decrease in the modulus of elasticity of hair shafts in premature neonates compared to full-term ones, potentially due to differences in disulphide bonds or microfibril arrangement.
February 2025 in “Cureus” This study focused on developing and validating standardized methods to reliably assess hair growth and scalp health in androgenetic alopecia, finding significant differences in hair parameters such as vellus and terminal hair counts, density, and thickness between affected and standardized areas.
October 2023 in “Asian journal of pharmaceutical and clinical research” In this study, researchers used trichoscopy to establish standardized findings for normal hair and scalp characteristics in 360 healthy males, noting significant age-related differences in hair diameter variability and identifying potential pathological indicators like colored dots and scarring not present in healthy individuals.
January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified non-structural proteins in preschool children's scalp hair that suggest potential biomarkers for brain development, immune function, and stress response with heritability and age-related differences.
1 citations
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November 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that intralesional triamcinolone acetonide at both 5 mg/mL and 10 mg/mL concentrations had similar effectiveness and safety for treating patchy alopecia areata on the scalp, with no significant difference in response rates or side effects between the two dosage groups.
1 citations
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January 2003 in “Benjamins eBooks” This study found no significant difference in hair cortisol concentrations between sows confined in farrowing crates and those in loose-housing systems, suggesting confinement may not affect chronic stress levels.
June 2018 in “The Journal of Sexual Medicine” This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.
10 citations
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January 2012 in “Journal of biomedical optics” This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.
9 citations
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June 2017 in “Journal of Cutaneous Pathology” This study found that follicular acantholysis is a common histopathological feature in pemphigus, with differences in depth between pemphigus vulgaris and pemphigus foliaceus lesions that may aid in diagnosis.
This study provides genomic and epigenomic insights into the white wax scale insect, highlighting high methylation levels and differential hormone profiles linked to its sexual dimorphism and developmental differences.
August 2026 in “Clinical and Translational Science” This study evaluated two bimatoprost 1% formulations for androgenetic alopecia in men, finding both formulations achieved effective drug concentrations in the scalp with no significant differences between them, and were well tolerated over the 14-day application period.
30 citations
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July 2000 in “PubMed” This study used advanced analytical techniques to reveal that proteins and lipids are distributed unevenly in hair, with distinct structural differences depending on their location within the fiber.
4 citations
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February 2017 in “Archives of Aesthetic Plastic Surgery” This study compared single and double-layer wound closure in hair restoration surgery and found no significant difference in scar size or quality. Single-layer closure was faster, less costly, and had better scar mobility, according to the researchers' report.
1 citations
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February 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study used social media data to identify more and milder COVID-19 symptoms than clinical research and to map symptom evolution over 27 months, highlighting differences between the Delta and Omicron periods.
8 citations
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March 2023 in “BMC Research Notes” This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.
February 2026 in “Journal of Cosmetic Dermatology” In this study, researchers found that combining cryotherapy with triamcinolone injections is equally effective as triamcinolone alone for treating patchy alopecia areata on the scalp and face, with no significant difference in outcomes between the two methods.
22 citations
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April 2020 in “Frontiers in Cellular and Infection Microbiology” This study found significant differences in scalp microbiome composition and volatile organic metabolites between individuals with alopecia areata and healthy controls, suggesting potential microbiome-related therapeutic interventions for hair growth disorders.