36 citations
,
September 1996 in “PubMed” This study found that dermal papilla and dermal sheath cells from human scalp tissue differ from interstitial dermal fibroblasts in morphology and produce varying levels of TGF-beta 2.
1 citations
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June 2024 in “BMC Oral Health” In this study, autologous platelet concentrates and topical steroids similarly reduced lesion size, Thongprasom scale, and pain in oral lichen planus patients, suggesting autologous platelet concentrates as a potential alternative treatment.
April 2025 in “International Journal of Dermatology” This study found that Black patients with alopecia areata showed an average 20% reduction in scalp involvement after JAK inhibitor therapy, indicating positive treatment outcomes in this group.
July 2016 in “Journal of Investigative Dermatology” R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.
This study found that adipose derived stem cells in areas of alopecia in patients with androgenetic alopecia showed different levels of various signaling proteins compared to other scalp and periumbilical regions.
January 2008 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study found that the gene for the enzyme aromatase is expressed in scalp hair follicles of women and is negatively correlated with LH levels, potentially reflecting the hormonal environment of hair follicles in PCOS.
18 citations
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January 1994 in “Skin Pharmacology and Physiology” This review discusses the enzyme levels involved in dihydrotestosterone formation in androgenetic alopecia patients and reports no new results; the authors suggest these differences may lead to better treatments for men and women.
8 citations
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September 2008 in “Medical Hypotheses” This article proposes a novel hypothesis that androgenetic alopecia may be mainly caused by skull bone expansion affecting blood supply to hair follicles rather than differences in individual follicle programming, and calls for more genetic research into skull development.
September 2025 in “Journal of Cosmetic Dermatology” This study found that both PRP injections and microneedling treatments significantly improved hair count and thickness in patients with androgenetic alopecia, without significant differences between the two methods. Microneedling also enhanced patient satisfaction and treatment tolerance.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This randomized controlled trial found that intralesional vitamin D3 was as effective and safe as intralesional triamcinolone acetonide for treating patchy alopecia areata on the scalp, with no significant influence from serum vitamin D levels on treatment response.
January 2025 in “International Journal of Dermatology” This study observed that indigenous South Africans with natural afro-textured hair have lower hair densities, varying shaft diameters, and distinct follicular unit patterns compared to other racial groups, with significant gender differences in some parameters, highlighting the need for tailored reference values in clinical settings.
28 citations
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January 2012 in “International Journal of Trichology” This study observed that specific trichoscopic features like white peripilar signs, scalp pigmentation, and focal atrichia are associated with advanced female pattern hair loss in Fitzpatrick skin type III patients.
22 citations
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January 2020 in “PeerJ” This study suggests that keratin peptide signatures in human hair shafts could potentially be used to distinguish gender and ethnicity, though further research on a larger scale is needed.
4 citations
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October 2023 in “Plastic & Reconstructive Surgery Global Open” This paper notes the rising trend of cosmetic surgery in Japan and emphasizes the future importance of developing a large-scale database to provide more accurate and beneficial information. Results are not reported.
4 citations
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February 1995 in “Journal of Clinical Dermatology” This study observed an increasing trend of young patients with androgenetic alopecia visiting dermatologists, with genetic factors and abnormal androgen metabolism in the scalp contributing to its development.
January 2026 in “The Breast Journal” This study found distinct symptom clusters in women with Stage I and Stage III nonmetastatic breast cancer, revealing differences in symptom prevalence and intensity, which could guide personalized supportive care strategies to improve quality of life.
May 2023 in “JAAD international” This study evaluated the clinical outcomes of using tattoo equipment to deliver a combination of minoxidil and dutasteride directly to the scalp over three sessions for treating male androgenetic alopecia, but results are not reported in the abstract.
1 citations
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January 2015 in “Hair therapy & transplantation” This study found that dutasteride increased hair growth metrics significantly more than finasteride in Korean men with AGA, but a meta-analysis suggests no overall significant efficacy difference between the two drugs.
36 citations
,
November 2009 in “Journal of Investigative Dermatology” This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.
23 citations
,
October 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study found that measuring cortisol in human hair can reflect increased cortisol production for up to six months, with the highest concentration in hair closest to the scalp.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
2 citations
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January 2003 in “PubMed” This study found that in individuals with androgenetic alopecia, the expression of apoptosis-related markers differed significantly between affected and unaffected scalp areas.
2 citations
,
February 1983 in “International Journal of Cosmetic Science” This study found that both hard and soft selenium disulphide-based detergents significantly increased triglyceride levels in human hair, suggesting enhanced sebum production with reduced lipolytic activity, but showed no significant differences between their effects.
1 citations
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February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
April 2026 in “Research Square” In this study, trichoscopic examination revealed that variations in hair diameter were more common in certain types of alopecia affecting the frontal scalp, suggesting the importance of evaluating the entire scalp for accurate diagnoses, although limitations include a single center design and small sample size.
May 2025 in “ID on line REVISTA DE PSICOLOGIA” This study evaluated the effects of pumpkin seed oil and rosemary essential oil combined with electrotherapy on androgenetic alopecia in stressed young women, finding no statistically significant differences between treatment groups and suggesting further research is needed to assess the oils' efficacy.
January 2024 in “Pan African Medical Journal” This study aimed to document and compare the prevalence and characteristics of hair loss in patients with systemic lupus erythematosus, noting the differences in trichoscopic and histopathologic evaluations between those with and without alopecia. Results are not reported.
December 2022 in “Plastic and Reconstructive Surgery” In this study, PRPF treatment was more effective than PRP alone in improving hair count and hair quality in androgenetic alopecia patients, with PRPF showing significant improvements in various hair growth parameters and having no statistical differences observed in the placebo group.
59 citations
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November 2018 in “Psychoneuroendocrinology” This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.
58 citations
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December 2020 in “Mayo Clinic Proceedings” This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.