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120-150 / 1000+ resultsresearch The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms
![Pharmacologic interventions in aging hair](/images/research/96d3bb4d-98db-427e-aeb8-bc03169d0c80/small/20430.jpg)
research Pharmacologic interventions in aging hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Development and optimization of finasteride-cinnamon oil-loaded ethanol-free microemulsions for transdermal delivery
![Potential application of PBM use in hair follicle organoid culture for the treatment of androgenic alopecia](/images/research/0dec6199-a576-4efa-9cbe-c4f8b2b7766b/small/20554.jpg)
research Potential application of PBM use in hair follicle organoid culture for the treatment of androgenic alopecia
Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
![Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study](/images/research/4df7041b-dea0-4e29-8ea9-127869f4069c/small/20565.jpg)
research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
research A microfluidic application for mass production of drug-loaded polymeric microspheres for a long-acting injectable with IVL-DrugFluidic®, a novel microfluidic microsphere manufacturing platform technology
research Literature Review: Topical Finasteride: To Use or Not to Use?
research Male pattern baldness and prostate cancer risk in a population-based case–control study
Men who start losing hair at age 30 may have a lower risk of prostate cancer.
research Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics
research Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women
research Expert consensus on the management of androgenetic alopecia in India
![A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors](/images/research/e2058ce5-dc5d-44b5-b33d-31c1fb95ef65/small/4242.jpg)
research A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors
The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
![Cause of Androgenic Alopecia](/images/research/fac986d6-78fa-48cf-9154-cf2a1bf9e4c2/small/12278.jpg)
research Cause of Androgenic Alopecia
Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.
![Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture](/images/research/51ba93e3-a0f8-4ee5-8e8e-8909321bbb3a/small/12146.jpg)
research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture
Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
![The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen](/images/research/01842126-6440-430d-b7a8-ecdeaa8ca766/small/15535.jpg)
research The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen
Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
![Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage](/images/research/d9411813-4369-4dbd-8a53-4c6adcc8d42e/small/18944.jpg)
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
![Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells](/images/research/ef0245fd-c1fd-4821-a375-b8d4a356aaaa/small/15180.jpg)
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
![TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles](/images/research/c1ebdb62-0361-4785-a385-4afc68f8b583/small/25917.jpg)
research TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
![New drugs under investigation for the treatment of alopecias](/images/research/e1768a16-0d73-4432-ab37-375532a53150/small/15945.jpg)
research New drugs under investigation for the treatment of alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
![The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin](/images/research/0495ef1b-4e23-45c0-9762-502d6617229b/small/13015.jpg)
research The Non-Cosmetic Dermatological Use of Botulinum Neurotoxin
Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
![An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia](/images/research/5adee3f9-e2d9-4605-9c57-c4b6ea971eb8/small/2512.jpg)
research An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia
Oral finasteride works better than topical minoxidil for hair growth, both are safe.
![Hair Growth: Focus on Herbal Therapeutic Agent](/images/research/c2f13e09-9ada-4ce1-8d9c-771dd049952b/small/14255.jpg)
research Hair Growth: Focus on Herbal Therapeutic Agent
Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
![THE USE OF DERMAL PAPILLA CELLS IN STUDIES OF NORMAL AND ABNORMAL HAIR FOLLICLE BIOLOGY](/images/research/f85a529c-b7d4-4b9e-8a10-7b7b88e862d0/small/23291.jpg)
research THE USE OF DERMAL PAPILLA CELLS IN STUDIES OF NORMAL AND ABNORMAL HAIR FOLLICLE BIOLOGY
Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.
![Evaluation of Animal Models Suitable for Hair Research and Regeneration](/images/research/ecfb6de3-590c-4f9e-a2ab-7904e3d88edf/small/17925.jpg)
research Evaluation of Animal Models Suitable for Hair Research and Regeneration
Animal models, especially mice, are essential for advancing hair loss research and treatment.
![Hair growth and rejuvenation: An overview](/images/research/e5134862-8e0f-49b0-9d89-b4f2a4e8eeda/small/14907.jpg)
research Hair growth and rejuvenation: An overview
The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
![Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach](/images/research/969315fa-6a43-4e35-8848-acdf703afc8a/small/4338.jpg)
research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach
NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.
![Topical Formulations Containing Finasteride. Part II: Determination of Finasteride Penetration into Hair Follicles using the Differential Stripping Technique](/images/research/ba11301b-dc4f-4102-bf1d-9bb25a8c689b/small/3477.jpg)
research Topical Formulations Containing Finasteride. Part II: Determination of Finasteride Penetration into Hair Follicles using the Differential Stripping Technique
Formulation P-08-016 better targets hair follicles for baldness treatment.
![Persistent Gynecomastia due to Short-term Low-dose Finasteride for Androgenetic Alopecia](/images/research/bc9d1fdd-b5b0-4602-9402-92ceb63a99da/small/26954.jpg)
research Persistent Gynecomastia due to Short-term Low-dose Finasteride for Androgenetic Alopecia
A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.