June 2024 in “Journal of Clinical Medicine” This case study and literature review highlights a chemical burn from hair dye experienced by a 17-year-old girl, resulting in a long-term scalp ulcer. It emphasizes the need for careful consideration of scalp complications and a multidisciplinary treatment approach in hair dye procedures.
January 2016 in “International archives of medicine” In this study, a significant relationship was observed between hair coloring and both hair damage and scalp problems among students at the University of Sumatera Utara.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed a herbal mehendi gel using natural plant-based ingredients aimed at providing sustainable hair coloring and scalp care. The formulation demonstrated beneficial properties including natural hair coloring, scalp conditioning, antimicrobial activity, antioxidant action, and safety with no observed skin irritancy.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal mehendi gel formulated for natural hair coloring and scalp care, finding it safe for topical use and demonstrating benefits like natural coloring and scalp conditioning.
May 2023 in “Health science reports” This review discusses the harmful effects of coloring shampoos containing trihydroxybenzene on the scalp-skin barrier and emphasizes the need for safer ingredient selection to prevent side effects.
17 citations
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January 2013 in “International Journal of Cosmetic Science” This study found that individuals who perceive their hair health as poor tend to have higher levels of metals on their hair, emphasizing the impact of environmental metal exposure.
December 2025 in “Journal of Pharma Insights and Research.” This study explains the formulation and evaluation of a natural polyherbal shampoo, which effectively colors hair and provides conditioning without the dermal and systemic toxicity risks of synthetic dyes, offering an effective alternative to conventional products.
150 citations
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July 2001 in “Clinics in dermatology” This article discusses hair care practices and hair cosmetics in managing alopecia but reports no new clinical findings; it emphasizes the importance of scalp health and good patient-physician communication.
51 citations
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July 2008 in “Dermatologic Therapy” This article proposes two new categories of cicatricial alopecia—“unstable” and “stable”—and suggests surgical excision as preferred over hair transplantation, especially for unstable cases.
4 citations
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July 2016 in “Journal of cosmetic dermatology” This review discusses the potential risks and effects of chemical relaxers on hair and scalp health, reporting no new clinical results; the authors emphasize dermatologist guidance to mitigate these issues.
This study developed a natural herbal hair dye powder using Eclipta prostrata, Nigella sativa, and Aloe Vera, which offers safe and environmentally friendly hair coloring while avoiding harmful effects associated with conventional dyes.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the development and benefits of herbal hair dye formulations using medicinal plants like henna and indigo, noting their potential as safer, eco-friendly alternatives to synthetic dyes due to their nourishing and protective properties for hair and scalp.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal hair dyes made from medicinal plants like henna and indigo offer a promising natural alternative to synthetic hair colorants, potentially reducing side effects while providing additional benefits such as hair nourishment and scalp protection.
March 2025 in “International Journal of Advanced Research in Science Communication and Technology” This study explores the potential of herbal hair dyes as eco-friendly alternatives to synthetic dyes, highlighting their natural coloring ability and additional benefits like scalp nourishment and hair strengthening, while evaluating factors such as pH, spreadability, and color fastness.
This study evaluated various herbal blends of powdered leaves, including Henna and Indigo, for their coloring and sensitivity reactions, finding Henna and Indigo to be effective natural colorants for achieving a reddish-brown hair color with better retention than marketed herbal hair dyes.
In this study, researchers developed a standardized Ayurvedic hair pack using natural ingredients like Shikakai and Amla and confirmed its safety and pH suitability; they concluded it could be a scientifically validated alternative to synthetic hair products.
January 2004 in “Linchuang pifuke zazhi” This case report describes a young man who suffered from secondary cicatrical alopecia due to a steam cap burn at a hair salon, with no improvement after 13 months of various treatments until surgical excision.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit and other natural ingredients, reporting that the dye provided satisfactory color, stability, scalp pH compatibility, and did not cause irritation, also demonstrating antioxidant and antimicrobial properties that benefit scalp health.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit, finding it to be a safe, effective, and environmentally friendly alternative to synthetic dyes, with added antioxidant and antimicrobial benefits for scalp health.
210 citations
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May 2006 in “The FASEB journal” This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.
13 citations
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January 2010 in “Advances in Biochemical Engineering / Biotechnology” This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.
1 citations
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October 2021 in “International journal of pharmaceutics and drug analysis” This study found that a herbal shampoo containing Aloe Vera and essential oils performed better in tests for smoothness, shine, and conditioning compared to a marketed shampoo.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal nanoemulgel-based hair dyes, incorporating natural ingredients, enhance dye penetration and retention while providing additional hair and scalp health benefits compared to conventional dyes, though further studies are needed to confirm long-term safety and efficacy.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that herbal nanoemulgel-based hair dyes, enriched with natural ingredients, improve dye penetration and retention and offer additional hair and scalp benefits compared to conventional dyes, although further research is necessary to verify their safety and efficacy for long-term use.
6 citations
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March 2015 in “Journal of The American Academy of Dermatology” This article discusses the diagnostic challenges of evaluating hair and scalp conditions in patients using hair dye, emphasizing how dyes can mimic different pathologies and lead to contact dermatitis.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a herbal hair dye gel using natural ingredients like henna and amla, which was found to provide natural color, improve hair texture, and clean the scalp without causing irritation, making it a safe and effective alternative to chemical hair dyes.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a herbal hair dye gel made from natural ingredients like henna and amla showed promising results in providing natural color and hair health benefits without causing irritation, offering a safer alternative to chemical hair dyes.
November 2017 in “Koubunshi rombunshuu/Kōbunshi ronbunshū” In this study, treatments using a shampoo and conditioner with hematin helped repair damaged hair by depositing a cuticle-like structure, straightening hair as observed through electron microscopy.
2 citations
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June 1997 in “The American Journal of Cosmetic Surgery” This article discusses methods for camouflaging surgical sites after hair transplant procedures and presents no new clinical findings.
16 citations
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December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.